Immunofluorescence staining of the muscle tissue of a chronically diseased human heart under the confocal microscope. Two proteins in the sarcomeres, which give the tissue the characteristic striation pattern, were marked with antibodies and visualized by different fluorophore-conjugated antibodies: titin appears red and actinin green; the nuclei were stained blue.
Immunofluorescence staining of the muscle tissue of a chronically diseased human heart under the confocal microscope. Two proteins in the sarcomeres, which give the tissue the characteristic striation pattern, were marked with antibodies and visualized by different fluorophore-conjugated antibodies: titin appears red and actinin green; the nuclei were stained blue. Linke Lab Immunofluorescence staining of the muscle tissue of a chronically diseased human heart under the confocal microscope. Two proteins in the sarcomeres, which give the tissue the characteristic striation pattern, were marked with antibodies and visualized by different fluorophore-conjugated antibodies: titin appears red and actinin green; the nuclei were stained blue. A healthy heart beats 50 to 100 times a minute and pumps 8,000 litres of blood around our body every day. A precondition for this function is the elasticity of the cardiac walls, which dilate as blood flows in (diastole) and contract again as the blood flows out (systole). Millions of tiny cavities in the heart muscle fibres, the sarcomeres, are responsible for this movement.
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