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Bioinformatics team develops method that enables fast and confident identification of small molecules More than a third of all medicines available today are based on active substances from nature and a research team from the University of Jena has developed a procedure to identify small active substance molecules much more quickly and easily.
MHH research team demonstrates how inflammatory cells improve the function of diseased heart muscle cells Heart failure or cardiac insufficiency is one of the most common causes of death in Germany and is caused by heart attacks, high blood pressure or heart valve defects. The heart is then no longer able to pump a sufficient amount of blood through the body and supply organs, muscles or other tissues with enough oxygen and nutrients.
Polyreactive antibodies as markers for autoimmune hepatitis Autoimmune hepatitis (AIH) is a chronic liver inflammation that is triggered by an immunological malfunction. In this case, the immune system falsely recognises the patient's own liver cells as "foreign to the body". The symptoms of this rare liver disease are unspecific, and the exact cause is not yet known.
Research team including Göttingen University observes charged particles 70 percent faster than uncharged Solar prominences hover above the visible solar disk like giant clouds, held there by a supporting framework of magnetic forces, originating from layers deep within the Sun. The magnetic lines of force are moved by ever-present gas currents - and when the supporting framework moves, so does the prominence cloud.
Antibiotics help us to treat bacterial infections and save millions of lives each year. But they can also harm the helpful microbes residing in our gut, weakening one of our body's first lines of defence against pathogens and compromising the multiple beneficial effects our microbiota has for our health.
Urbanisation appears to be another key factor for insect decline. This is shown by a study in which the impact of climate and land use on insects was disentangled for the first time. Worldwide, the quantity and diversity of insects are declining: scientists have reported more and more evidence for this in recent years.
Protective role of cells in overwintering fungi
Göttingen researchers find cells involved in sexual development produce chemicals that deter hungry predators Scientists have discovered a new role for cells that are known to nurture the reproductive structures in the fungus Aspergillus nidulans through the winter. The findings suggest that Hülle cells in this fungus also play a key part in its chemical defence strategies to ward off hungry predators.
Göttingen researchers find cells involved in sexual development produce chemicals that deter hungry predators Scientists have discovered a new role for cells that are known to nurture the reproductive structures in the fungus Aspergillus nidulans through the winter. The findings suggest that Hülle cells in this fungus also play a key part in its chemical defence strategies to ward off hungry predators.
The oldest known footprints of pre-humans were found on the Mediterranean island of Crete and are at least six million years old, says an international team of researchers from Germany, Sweden, Greece, Egypt and England, led by Tübingen scientists Uwe Kirscher and Madelaine Böhme of the Senckenberg Center for Human Evolution and Palaeoenvironment at the University of Tübingen.
How a small RNA and a small protein regulate the metabolism of cholera bacteria and the production of the cholera toxin The human gut is a multi-species habitat that can control our health and well-being. Bacteria, viruses and microbial fungi are part of this complex microbial community and help us with our digestion and immune defense.
International research team led by University of Göttingen finds atomically-thin carbon generates its own magnetic field Usually, the electrical resistance of a material depends very much on its physical dimensions and fundamental properties. Under special circumstances, however, this resistance can adopt a fixed value that is independent of the basic material properties and "quantised" (meaning that it changes in discrete steps rather than continuously).
An international research team led by Professor Stephanie Grond from the Institute of Organic Chemistry at the University of Tübingen has found that the natural substance collinolactone reduces artificially-induced stress on nerve cells, protecting them from the kind of damage that occurs in neurodegenerative diseases.
Protein causes more severe cancer disease in men A remarkable number of life-threatening diseases manifest more severely in males than in females. One current example is COVID-19 caused by SARS CoV-2. Another example is the significantly higher risk of severe cancer progression for men. A research team at the Technical University of Munich (TUM) has now discovered a molecular cause for this difference between sexes.
Novel Process for Industrial Production of Basic Chemicals
Researchers at Freie Universität Berlin developed new approach for producing phosgene Scientists at Freie Universität Berlin have developed a new type of process for the industrial production of basic chemicals. They found a new approach to phosgene, opening up completely new possibilities in the production of raw materials.
Researchers at Freie Universität Berlin developed new approach for producing phosgene Scientists at Freie Universität Berlin have developed a new type of process for the industrial production of basic chemicals. They found a new approach to phosgene, opening up completely new possibilities in the production of raw materials.
Researchers develop imaging methods to examine bodily processes from the individual building blocks to the whole system / Proof-of-principle study on SNAP-tag technology published in the journal "Chemical Communications" Video in English, subtitles available in English and German. Processes and structures within the body that are normally hidden from the eye can be made visible through medical imaging.
Bombardment of Planets in the Early Solar System
Studies of the asteroid Vesta provide new findings on the formation of Earth-like planets The largest asteroid in our Solar System - Vesta - was exposed to an extensive series of impacts by large rocky bodies much earlier than previously assumed. Researchers of an international collaboration, including earth scientists from Heidelberg University and Freie Universität Berlin, reached this conclusion based on analyses of Vesta meteorites, numerical simulations, and observations carried out with the space probe Dawn in 2011 and 2012.
Studies of the asteroid Vesta provide new findings on the formation of Earth-like planets The largest asteroid in our Solar System - Vesta - was exposed to an extensive series of impacts by large rocky bodies much earlier than previously assumed. Researchers of an international collaboration, including earth scientists from Heidelberg University and Freie Universität Berlin, reached this conclusion based on analyses of Vesta meteorites, numerical simulations, and observations carried out with the space probe Dawn in 2011 and 2012.
Chemists at the University of Jena developed methods for manufacturing glasses from non-melting compounds Chemists at the University of Jena developed a way of melting normally unmeltable metal-organic framework compounds - so-called MOFs. This allows the melt-based production of glass components for applications in energy and environmental technology.
Increased economic benefits and resilience with collaborative management of the Nile’s Grand Ethiopian Renaissance Dam
New research linking water and economic modelling shows that coordinated filling and operation of the Grand Ethiopian Renaissance Dam (GERD) increases economic benefits and resilience in the riparian countries. In the Nile Basin region, eleven African countries are economically dependent on the river, though differently.
New research linking water and economic modelling shows that coordinated filling and operation of the Grand Ethiopian Renaissance Dam (GERD) increases economic benefits and resilience in the riparian countries. In the Nile Basin region, eleven African countries are economically dependent on the river, though differently.
09/24/2021 Israeli and German researchers have developed a way to force an array of vertical cavity lasers to act together as a single laser - a highly effective laser network the size of a grain of sand. The findings are presented in a new joint research paper published online by the prestigious journal Science on Friday, September 24.
Researchers at Göttingen University use computer simulation to investigate models of living systems Living or biological systems cannot be easily understood using the standard laws of physics, such as thermodynamics, as scientists would for gases, liquids or solids. Living systems are active, demonstrating fascinating properties such as adapting to their environment or repairing themselves.
09/23/2021 The higher the biological diversity in an ecosystem, the better the important processes there function. A heterogeneous environment promotes this effect, while intensive land use weakens it, as a new study shows. Microorganisms, plants, and animals accomplish great feats every day. For example, by decomposing material, producing plant biomass, or pollinating flowers, they keep nature 'up and running,' thereby securing the livelihood of humans.
News from the Lab is a selection of science news that are significant or interesting for a broad readership.
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