Lupus trigger discovered

Researchers were able to trace a form of the autoimmune disease lupus back to a single mutation. In this cell, Toll-like receptor 7 was stained pink in order to analyse its amount and position under the microscope. The cell is healthy and the amount of Toll-like receptor is normal. The situation is different in the immune cells of lupus patients, which have a significantly increased number of receptors, whereby the body's own genetic material is recognised and the chronic inflammation of lupus is triggered. MPI f. Infection Biology/ Fenja Blank - Sometimes a single mutation in our genetic make-up is enough to cause disease. This is also the case with the autoimmune disease lupus. Lupus causes severe inflammation throughout the body and can have a serious impact on the lives of those affected.