Sugars influence cell-to-surface adhesion

Using TIRF microscopy, Flagella-mediated adhesion can be visualized and analysed. Lara Hoepfner How can cells adhere to surfaces and move on them? This is a question which was investigated by an international team of researchers headed by Prof. Michael Hippler from the University of Münster and Prof. Kaiyao Huang from the Institute of Hydrobiology (Chinese Academy of Sciences, Wuhan, China). The researchers used the green alga Chlamydomonas reinhardtii as their model organism. They manipulated the alga by altering the sugar modifications in proteins on the cell surface. As a result, they were able to alter the cellular surface adhesion, also known as adhesion force. The results have now been published in the open access scientific journal "eLife'. Background and methodology In order to move, the green alga has two thread-like flagella on its cell surface.