Starvation Causes Cell Remodeling

New study on "starvation response" by Freie Universität professor of pharmacology published in Science / Joint press release with the Leibniz-Forschungsinstitut für Molekulare Pharmakologie. Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has now discovered a previously unknown mechanism for how this "starvation response" is triggered and what can inhibit it. The results have been published in the renowned international journal Science ( https://www.science.org/doi/10.1126/science.abq5209 ). In order for the body to function, cells need a constant supply of energy. During phases of starvation, when no nutrients are taken up from food, the cellular metabolism must adapt to ensure a sustained supply of energy. Researchers from the FMP have gained new insights into this fundamental mechanism in human cells while investigating a rare genetic muscular disorder - X-linked centronuclear myopathy (XLCNM).