The bacterium Vibrio cholerae has a defense system against bacteriophages called CBASS. This phage defense mechanism makes the cholera pathogen sensitive to antibiotics
The bacterium Vibrio cholerae has a defense system against bacteriophages called CBASS. This phage defense mechanism makes the cholera pathogen sensitive to antibiotics Bacteria have an immune system that protects them against viruses known as bacteriophages. A research team from the Universities of and Würzburg has now shown how this immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae . The immune system is the reason why this bacterium is particularly sensitive to one of the oldest known classes of antibiotics - the antifolates. The team's findings have been published in the latest issue of Nature Microbiology . Vibrio cholerae causes severe cholera outbreaks worldwide and is endemic in many developing countries. Its immune system is made up of several molecular defense systems which protect the bacterium against attacks by various bacteriophages.
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