Henriette Uhlenhaut and her team examining the effects of cortisone to create the foundation for the development of drugs with similar beneficial effects but fewer side effects. (Photo: A. Heddergott / TUM)
Henriette Uhlenhaut and her team examining the effects of cortisone to create the foundation for the development of drugs with similar beneficial effects but fewer side effects. (Photo: A. Heddergott / TUM) DNA binding is essential for effectiveness of steroids - Many people use cortisone of a regular basis. It is used for treating rheumatism, asthma, multiple sclerosis, or even COVID-19. Steroidal medication such as cortisone is highly effective but also possesses severe side effects. Henriette Uhlenhaut, professor at Technical University of Munich (TUM), and her team are examining the beneficial effects of cortisone in order to lay the groundwork for the development of similar drugs with fewer side effects. A group of scientists around Henriette Uhlenhaut , Professor for Metabolic Programming at TUM School of Life Sciences in Freising-Weihenstephan and researcher in the field of Molecular Endocrinology at Helmholtz Zentrum München is working with so-called glucocorticoids. These are steroidal hormones such as cortisone, which are released by the adrenal glands every day before waking up or whenever a person is subjected to stress.
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