How platelets help resolve lung inflammation

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Platelets (red) interacting with regulatory T cells (yellow) in the bacterially
Platelets (red) interacting with regulatory T cells (yellow) in the bacterially inflamed lung tissue of a mouse. Researchers examined the living tissue using confocal fluorescence microscopy. © Rossaint et al./JExpMed 2021
Platelets ( red ) interacting with regulatory T cells ( yellow ) in the bacterially inflamed lung tissue of a mouse. Researchers examined the living tissue using confocal fluorescence microscopy. Rossaint et al./JExpMed 2021 - Scientists at the University of Münster provide new insights into interactions between platelets and white blood cells in mice / Study published in the Journal of Experimental Medicine Treating patients with acute respiratory failure is a constant challenge in intensive care medicine. In most cases, the underlying cause is lung inflammation triggered by a bacterial infection or - more rarely, despite being frequently observed at present due to the corona pandemic - a viral infection. During the inflammation, cells of the immune system - the white blood cells - migrate to the lungs and fight the pathogens. At the same time, however, they also cause "collateral damage" in the lung tissue. If the inflammatory reaction is not resolved in time, this can result in chronic inflammation with permanent impairment of lung function.
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