Simplified method for calibrating optical tweezers: Broadband measurement of viscoelasticity with reduced measurement time

A microparticle held with optical tweezers in the microscope. Inset: Illustratio
A microparticle held with optical tweezers in the microscope. Inset: Illustration of the held particle (magnified); shown in red is the light of the infrared laser used. © Pascal Runde
A microparticle held with optical tweezers in the microscope. Inset: Illustration of the held particle (magnified); shown in red is the light of the infrared laser used. Pascal Runde Measurements of biomechanical properties inside living cells require minimally invasive methods. Optical tweezers are particularly attractive as a tool. It uses the momentum of light to trap and manipulate microor nanoscale particles. A team of researchers led by Cornelia Denz from the University of Münster has now developed a simplified method to perform the necessary calibration of the optical tweezers in the system under investigation. Scientists from the University of Pavia in Italy were also involved.
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