CaAR in a breast cancer cell after perforation of the plasma membrane with a needle (atomic force microscope). Images created 0, 30 and 60 seconds after stimulation (perforation).
- Wales P. et al.
A stressful job, trouble with the children and a near-empty bank account. When everything starts to get too much again, it can help to make a fresh start. If cells are under a lot of stress, for example as a result of injuries, they also undergo a fundamental reorganization. It's all about their cytoskeleton, which again and again forms new structures from many individual components in a highly flexible way, for example in order to support the cell or to transport molecular charges. A team headed by Prof. Roland Wedlich-Söldner at the Cells-in-Motion Cluster of Excellence at Münster University were able to shed light on this process in detail. The researchers showed that the "new beginning" undergone by the cells is important for repair and wound-healing processes, and that it might play a role too in cell migration, cancer and inflammations. The article has now been published in the journal eLife .
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