Ointment with DNA molecules combats allergic contact dermatitis

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Study by the University of Bonn shows that what are known as aptamers can be absorbed directly via the skin

Fluorescence microscopic imaging of the skin treated with the aptamer cream: - T
Fluorescence microscopic imaging of the skin treated with the aptamer cream: - The aptamers (here marked in pink) were applied to the top layer of the skin in the form of an ointment and also penetrate into the deeper dermal layers (nucleus: blue; antigen-presenting cells: green). Photo: Marlene Gottschalk all’images in original size .
Researchers at the University of Bonn have isolated a DNA molecule that is suitable for combating allergic contact dermatitis in mice. What is known as an aptamer binds to certain immune system messenger substances, rendering them ineffective. This even works if the active ingredient is applied to the skin in the form of an ointment. The working groups involved hope that aptamer creams such as this could also be suitable for treating other skin conditions. ...
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