International research team analyzed the genetic material of more than 5,000 severely affecteds
Rare gene mutations can significantly increase the risk of severe COVID-19 disease. An international research team with significant contribution of the University of Bonn compared the genetic material of 5,085 people with severe COVID-19 and more than 570,000 controls. The results showed that alterations in the gene TLR7, which is important for the immune defense in humans, lead to infections with a severe course. The findings have now been published in the journal PLOS GENETICS.
"TLR7 belongs to the Toll-like receptor family and recognizes pathogens, which is followed by subsequent activation ofthe innate immune system," says Dr. ...
