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Under the influence of the drug fluconazole, the fungus Candida albicans can change its mode of reproduction and thus become even more resistant. Scientists at the University of Würzburg report this in the journal mBio. The yeast Candida albicans occurs in most healthy people as a harmless colonizer in the digestive tract.

01/30/2019 Researchers at the Rudolf Virchow Center of the University of Würzburg have unveiled the molecular effectiveness of artemisinins. The findings could lead to drugs for diseases such as Alzheimer's, schizophrenia and epilepsy. Artemisinin is derived from the leaves and flowers of the annual mugwort (Artemisia annua) and has been used in traditional Chinese medicine for centuries.

Synthetic molecules are essential for many products in our lives: medicines, crop protection agents or special materials such as Teflon. These molecules have several components, which can be combined in a variety of ways, resulting in different properties. Both so-called piperidines and fluorinated groups are particularly important.

Scientists at Freie Universität Explore Alternative Routes to Drugs against Tumor Cells / Findings published in online journal "Nature Communications" No 002/2019 from Jan 08, 2019 Scientists at Freie Universität Berlin have discovered an alternative route to drugs against tumor cells. The group led by Jörg Rademann from the Institute of Pharmacy examined the protein STAT5, which is responsible for the aggressive growth of human leukemia cells.

Pharmacists and biochemists of the Friedrich Schiller University Jena, together with an international research team, have decoded the anti-inflammatory mechanism of vitamin E and its metabolites. The result shows value of personalised medicine. A patented drug candidate now being studied further. It is reputed to stop skin from aging, reduce joint degeneration in rheumatism and arthritis, and even protect against cancer and cardiovascular diseases.

08/20/2015 Abandoning expensive and toxic materials in chemical synthesis: This is the goal pursued by scientists at the University of Würzburg. In the magazine "Angewandte Chemie", they describe a new way to achieve this goal, a surprise included. Arylboronates are important base materials for the industrial fabrication of countless products, including pharmaceutical drugs, chemicals for agriculture or liquid crystals for displays.

06/17/2015 For the first time, Würzburg scientists have successfully bound multiple carbon monoxide molecules to the main group element boron. They report on their work in the latest issue of the scientific journal Nature. Scientists of Professor Holger Braunschweig's team of the Institute of Inorganic Chemistry at the University of Würzburg have successfully bound two carbon monoxide molecules (CO) to the main group element boron in a direct synthesis for the first time.