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Life Sciences - Paleontology - 05.01.2023
Life Sciences - Health - 05.01.2023 
New Type of Gene Scissors
Like a Swiss army knife: Researchers from Würzburg and the U.S. discover new type of CRISPR gene scissors. New publication in "Nature". Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens.
Life Sciences - Chemistry - 05.01.2023 
Formation of pores in mitochondrial membrane elucidated
Study by a team of researchers from Freiburg and Kyoto investigates formation of beta-barrel membrane proteins that make up the pores Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40 percent of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important role in medical research.
Life Sciences - Health - 04.01.2023 
Exercise Curbs Insulin Production
When a fruit fly starts walking or flying, its insulin-producing cells are immediately inhibited. This could be one explanation for why exercise promotes health. Insulin is an essential hormone for humans and many other living creatures. Its best-known task is to regulate sugar metabolism. How it does this job is well understood.
Life Sciences - 29.12.2022
Chemistry - Life Sciences - 21.12.2022 
’A lot of work was invested before I was able to control these reactions’
Dr Charlotte Teschers has developed an automated method for producing -glycomimetics- One project, one researcher and five years of intensive work: as part of her doctoral thesis, supervised by Prof. Ryan Gilmour at the Institute of Organic Chemistry, Dr. Charlotte Teschers has successfully developed a new method of producing complex, fluorinated sugars.
Life Sciences - Health - 21.12.2022 
How nerve and vascular cells coordinate their growth
Study by the Universities of Bonn and Heidelberg provides insights into a carefully choreographed dance Nerve cells need a lot of energy and oxygen. They receive both through the blood. This is why nerve tissue is usually crisscrossed by a large number of blood vessels. But what prevents neurons and vascular cells from getting in each other's way as they grow? Researchers at the Universities of Heidelberg and Bonn, together with international partners, have identified a mechanism that takes care of this.
Health - Life Sciences - 20.12.2022 
New gene mutation discovered in children in obesity research
A research team at the University of Leipzig Medical School has discovered a new mechanism associated with severe childhood obesity. A genetic alteration leads to an unusual expression of a gene related to the control of the feeling of hunger. Until now, this alteration has not been detected with general genetic diagnostics in obesity.
Life Sciences - 20.12.2022 
Rapid Evolution of Spermatogenesis
Heidelberg scientists decode the genetic foundations of rapid testicle evolution in mammals and humans Evolutionary pressure across male mammals to guarantee the procreation of their own offspring led to a rapid evolution of the testicle. Bioinformatic studies - conducted by an international team of researchers led by Henrik Kaessmann from the Center for Molecular Biology of Heidelberg University - show that this pressure particularly accelerated the evolution of later stages of sperm formation.
Health - Life Sciences - 20.12.2022 
New gene mutation in children
A research team at Leipzig University's Faculty of Medicine has discovered a new mechanism that is associated with severe obesity in children. This genetic rearrangement leads to an unusual expression of a gene involved in hunger control and is not detected by most routine genetic tests for obesity.
Life Sciences - Health - 19.12.2022 
New findings on memory impairment in epilepsy
Study by the University of Bonn elucidates a potential mechanism People with chronic epilepsy often experience impaired memory. Researchers at the University of Bonn have now found a mechanism in mice that could explain these deficits. The German Center for Neurodegenerative Diseases (DZNE) was also involved in the study.
Life Sciences - Pharmacology - 16.12.2022
Life Sciences - Pharmacology - 16.12.2022 
When hungry, the cell remodels
Body cells burn fat reserves when the supply of nutrients from food is interrupted. A team led by Volker Haucke of Freie Universität Berlin and the Leibniz Research Institute for Molecular Pharmacology (FMP) and Wonyul Jang of the FMP has now discovered a previously unknown mechanism for how this "starvation metabolism" gets going - and what can inhibit it.
Life Sciences - Health - 15.12.2022 
Cleft lip and palate: News from the genes
Researchers at the University of Bonn find clues to the causes of the condition Cleft lip and palate are among the most common congenital malformations, which are mainly due to genetic causes. It is not yet known exactly which genes are affected. A study led by the University of Bonn has now uncovered new correlations: New mutations near known genes such as SPRY1 could contribute to the increase in disease risk.
Life Sciences - 14.12.2022 
RNA sponge controls bacterial communication
Researchers from the Cluster of Excellence ,,Balance of the Microverse" and the University of Jena were able to identify an RNA sponge that controls the dynamics of quorum sensing and the associated formation of biofilms in the bacterium Vibrio cholerae. Cholerae bacteria do not form the disease-causing biofilm until they reach a certain cell density, which they determine using quorum sensing.
Health - Life Sciences - 14.12.2022 
Some cancer cells may not be as immortal as previously thought
Researchers use baker's yeast to study potential targets for fighting cancer cells Scientists at Johannes Gutenberg University Mainz (JGU) and the Institute of Molecular Biology (IMB) in Mainz may have discovered new insights into how cancer cells regulate the ends of their chromosomes, called telomeres.
Astronomy / Space Science - Life Sciences - 12.12.2022 
Space missions: Building blocks of life technically detectable on icy moons
Technically, it would be possible for future space missions to detect DNA, lipids and other bacterial components on icy moons with an ocean beneath the ice in our solar system - assuming these building blocks of life exist beyond Earth. This is the conclusion reached by an international team of scientists including Professor Abel's research group at Leipzig University.
Agronomy / Food Science - Life Sciences - 08.12.2022 
Agriculture makes the weed
How intensive agriculture turned a wild plant into a pervasive weed Agriculture is driving rapid evolutionary change, not just on farms, but also in wild species in the surroundings. New research shows how the rise of modern agriculture has turned a North American native plant, common waterhemp, into a problematic agricultural weed by mutations in hundreds of genes related to drought tolerance, rapid growth, and resistance to herbicides.
Health - Life Sciences - 07.12.2022
Life Sciences - Health - 06.12.2022 
How neurons regulate their excitability autonomously
Study by the University of Bonn elucidates important mechanism in the brain Nerve cells can regulate their sensitivity to incoming signals autonomously. A new study led by the University of Bonn has now discovered a mechanism that does just that. The German Center for Neurodegenerative Diseases and the Max Planck Institute for Neurobiology of Behavior were involved in the work.
Life Sciences
Results 81 - 100 of 978.
The vertebral column develops in the same way in modern animals as it did 300 million years ago
Ancient fossils reveal the evolutionary history of ossification in the spine of land vertebrates A study conducted by researchers from the Museum für Naturkunde in Berlin revealed the evolution of ossification patterns in the backbones of four-legged vertebrates. Antoine Verrière and his colleagues were able to reconstruct the patterns of how the bones in the vertebral column formed in the ancestor to all land vertebrates based on a large dataset of modern and fossil vertebrates with the inclusion of rare new data from the 300 Ma old reptile Mesosaurus tenuidens.
Ancient fossils reveal the evolutionary history of ossification in the spine of land vertebrates A study conducted by researchers from the Museum für Naturkunde in Berlin revealed the evolution of ossification patterns in the backbones of four-legged vertebrates. Antoine Verrière and his colleagues were able to reconstruct the patterns of how the bones in the vertebral column formed in the ancestor to all land vertebrates based on a large dataset of modern and fossil vertebrates with the inclusion of rare new data from the 300 Ma old reptile Mesosaurus tenuidens.
Like a Swiss army knife: Researchers from Würzburg and the U.S. discover new type of CRISPR gene scissors. New publication in "Nature". Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens.
Study by a team of researchers from Freiburg and Kyoto investigates formation of beta-barrel membrane proteins that make up the pores Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40 percent of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important role in medical research.
When a fruit fly starts walking or flying, its insulin-producing cells are immediately inhibited. This could be one explanation for why exercise promotes health. Insulin is an essential hormone for humans and many other living creatures. Its best-known task is to regulate sugar metabolism. How it does this job is well understood.
New study on the circadian clock of the fruit fly
Regulating the sleep-wake cycle: researchers demonstrate the importance of transporting a "clock protein" from the cell nucleus for temperature compensation The higher the temperatures, the faster physiological processes are. But there is an exception - the so-called circadian clock, which regulates the sleep-wake cycle in organisms.
Regulating the sleep-wake cycle: researchers demonstrate the importance of transporting a "clock protein" from the cell nucleus for temperature compensation The higher the temperatures, the faster physiological processes are. But there is an exception - the so-called circadian clock, which regulates the sleep-wake cycle in organisms.
Dr Charlotte Teschers has developed an automated method for producing -glycomimetics- One project, one researcher and five years of intensive work: as part of her doctoral thesis, supervised by Prof. Ryan Gilmour at the Institute of Organic Chemistry, Dr. Charlotte Teschers has successfully developed a new method of producing complex, fluorinated sugars.
Study by the Universities of Bonn and Heidelberg provides insights into a carefully choreographed dance Nerve cells need a lot of energy and oxygen. They receive both through the blood. This is why nerve tissue is usually crisscrossed by a large number of blood vessels. But what prevents neurons and vascular cells from getting in each other's way as they grow? Researchers at the Universities of Heidelberg and Bonn, together with international partners, have identified a mechanism that takes care of this.
A research team at the University of Leipzig Medical School has discovered a new mechanism associated with severe childhood obesity. A genetic alteration leads to an unusual expression of a gene related to the control of the feeling of hunger. Until now, this alteration has not been detected with general genetic diagnostics in obesity.
Heidelberg scientists decode the genetic foundations of rapid testicle evolution in mammals and humans Evolutionary pressure across male mammals to guarantee the procreation of their own offspring led to a rapid evolution of the testicle. Bioinformatic studies - conducted by an international team of researchers led by Henrik Kaessmann from the Center for Molecular Biology of Heidelberg University - show that this pressure particularly accelerated the evolution of later stages of sperm formation.
A research team at Leipzig University's Faculty of Medicine has discovered a new mechanism that is associated with severe obesity in children. This genetic rearrangement leads to an unusual expression of a gene involved in hunger control and is not detected by most routine genetic tests for obesity.
Study by the University of Bonn elucidates a potential mechanism People with chronic epilepsy often experience impaired memory. Researchers at the University of Bonn have now found a mechanism in mice that could explain these deficits. The German Center for Neurodegenerative Diseases (DZNE) was also involved in the study.
Starvation Causes Cell Remodeling
New study on "starvation response" by Freie Universität professor of pharmacology published in Science / Joint press release with the Leibniz-Forschungsinstitut für Molekulare Pharmakologie Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has now discovered a previously unknown mechanism for how this "starvation response" is triggered and what can inhibit it.
New study on "starvation response" by Freie Universität professor of pharmacology published in Science / Joint press release with the Leibniz-Forschungsinstitut für Molekulare Pharmakologie Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has now discovered a previously unknown mechanism for how this "starvation response" is triggered and what can inhibit it.
Body cells burn fat reserves when the supply of nutrients from food is interrupted. A team led by Volker Haucke of Freie Universität Berlin and the Leibniz Research Institute for Molecular Pharmacology (FMP) and Wonyul Jang of the FMP has now discovered a previously unknown mechanism for how this "starvation metabolism" gets going - and what can inhibit it.
Researchers at the University of Bonn find clues to the causes of the condition Cleft lip and palate are among the most common congenital malformations, which are mainly due to genetic causes. It is not yet known exactly which genes are affected. A study led by the University of Bonn has now uncovered new correlations: New mutations near known genes such as SPRY1 could contribute to the increase in disease risk.
Researchers from the Cluster of Excellence ,,Balance of the Microverse" and the University of Jena were able to identify an RNA sponge that controls the dynamics of quorum sensing and the associated formation of biofilms in the bacterium Vibrio cholerae. Cholerae bacteria do not form the disease-causing biofilm until they reach a certain cell density, which they determine using quorum sensing.
Researchers use baker's yeast to study potential targets for fighting cancer cells Scientists at Johannes Gutenberg University Mainz (JGU) and the Institute of Molecular Biology (IMB) in Mainz may have discovered new insights into how cancer cells regulate the ends of their chromosomes, called telomeres.
Technically, it would be possible for future space missions to detect DNA, lipids and other bacterial components on icy moons with an ocean beneath the ice in our solar system - assuming these building blocks of life exist beyond Earth. This is the conclusion reached by an international team of scientists including Professor Abel's research group at Leipzig University.
How intensive agriculture turned a wild plant into a pervasive weed Agriculture is driving rapid evolutionary change, not just on farms, but also in wild species in the surroundings. New research shows how the rise of modern agriculture has turned a North American native plant, common waterhemp, into a problematic agricultural weed by mutations in hundreds of genes related to drought tolerance, rapid growth, and resistance to herbicides.
Anatomical barriers shield the brain from SARS-CoV-2 invasion at vulnerable interfaces
Absence of evidence for neurotropism and neuroinvasion of several SARS-CoV-2 variants including Omicron A common symptom of COVID-19 is a partial or complete loss of smell. The virus infects sustentacular cells in the olfactory epithelium and is thought to impair thereby the activity of the sensory neurons in this epithelium.
Absence of evidence for neurotropism and neuroinvasion of several SARS-CoV-2 variants including Omicron A common symptom of COVID-19 is a partial or complete loss of smell. The virus infects sustentacular cells in the olfactory epithelium and is thought to impair thereby the activity of the sensory neurons in this epithelium.
Study by the University of Bonn elucidates important mechanism in the brain Nerve cells can regulate their sensitivity to incoming signals autonomously. A new study led by the University of Bonn has now discovered a mechanism that does just that. The German Center for Neurodegenerative Diseases and the Max Planck Institute for Neurobiology of Behavior were involved in the work.
