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Health - Life Sciences - 17.03.2020 
Blocking sugar structures on viruses and tumor cells
Coronavirus: University operations limited +++ make use of online services +++ many staff working from home +++ www.tum.de/corona Artificial sugar-binding protein may inhibit cell growth During a viral infection, viruses enter the body and multiply in its cells. Viruses often specifically attach themselves to the sugar structures of the host cells, or present characteristic sugar structures on their surface themselves.
Life Sciences - Health - 13.03.2020 
Analysis of whole brain vasculature
Coronavirus: University operations limited +++ make use of online services +++ many staff working from home Biochemical methods and AI show even the finest capillaries Diseases of the brain are often associated with typical vascular changes. Now, scientists at LMU University Hospital Munich, Helmholtz Zentrum München and at the Technical University of Munich (TUM) have come up with a technique for visualising the structures of all the brain's blood vessels - right down to the finest capillaries - including any pathological changes.
Life Sciences - Chemistry - 12.03.2020 
A molecular map for the plant sciences
First comprehensive map of the proteome of the model plant Arabidopsis thaliana Plants are essential for life on earth. They provide food for essentially all organisms, oxygen for breathing, and they regulate the climate of the planet. Proteins play a key role in controlling all aspects of life including plants.
Life Sciences - 06.03.2020
Environment - Life Sciences - 25.02.2020 
Eat or be eaten
Biodiversity increases the efficiency of energy use in grasslands Plants obtain their energy from the sun. Other beings rely on eating to survive. Yet how does the energy flow inside ecosystems function and are there differences between ecosystems with many species in comparison to those with few species' Researchers have now examined these questions using a holistic approach by evaluating data gathered through a large-scale biodiversity experiment.
Life Sciences - 21.02.2020
Life Sciences - Health - 20.02.2020
Computer Science - Life Sciences - 19.02.2020 
"A rethinking in the minds of researchers is necessary": Guest comments
The reproducibility of research results is one of the fundamental quality criteria in science. The demand for transparency of the scientific knowledge process aims to ensure the repeatability of scientific studies or experiments. The project "Opening Reproducible Research" (o2r) of the Institute for Geoinformatics of the University of Münster and the University and State Library of Münster deals with this topic.
Life Sciences - Chemistry - 13.02.2020
Life Sciences - Health - 12.02.2020 
Research team illuminates macrophages
Molecular switch in bone marrow stem cells helps research into inflammatory processes in the brain Life Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.
Life Sciences - 12.02.2020 
Lane change in the cytoskeleton
Transport proteins can switch between microtubule network and actin network Many amphibians and fish are able to change their color in order to better adapt to their environment. Munich-based scientists have now investigated the molecular mechanisms in the cytoskeleton necessary for this and revealed potential evolutionary paths.
Life Sciences - Health - 05.02.2020 
The invisibility cloak of a fungus
While viruses and bacteria regularly manage to infect the human organism, fungi only very rarely succeed. The reason for this is that the human immune system can recognize them very easily because their cells are surrounded by a solid cell wall of chitin and other complex sugars. Chitin is, so to speak, the alarm signal for our immune system, to which it reacts with a whole arsenal of defensive weapons.
Life Sciences - Agronomy / Food Science - 05.02.2020
Environment - Life Sciences - 30.01.2020 
Biological diversity as a factor of production
Relationship between the economic value of our ecosystems and biodiversity Can the biodiversity of ecosystems be considered a factor of production? A group of researchers under the direction of the Technical University of Munich (TUM) are studying the economic benefits that farmers and foresters can obtain by focusing on several species instead of just one.
Life Sciences - Physics - 29.01.2020 
Guardian angel of the eye
Protective protein in the eye lens affects protein oxidation The lens of the human eye comprises a highly concentrated protein solution, which lends the lens its great refractive power. Protective proteins prevent these proteins from clumping together throughout a lifetime. A team of scientists from the Technical University of Munich (TUM) has now uncovered the precise structure of the 'A-crystallin protein and, in the process, discovered an important additional function.
Life Sciences - Chemistry - 29.01.2020
Health - Life Sciences - 27.01.2020 
Gene scissors against incurable muscular disease
New gene correction therapy for Duchenne muscular dystrophy Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children, leaving them wheelchair-bound before the age of twelve and reducing life expectancy. Researchers at Technical University of Munich (TUM), Ludwig Maximilian University of Munich (LMU) and the German Research Center for Environmental Health (Helmholtz Zentrum München) have developed a gene therapy that may provide permanent relief for those suffering from DMD.
Life Sciences - Chemistry - 24.01.2020 
Deciphering the sugar code
Like animals and humans, plants possess a kind of immune system. It can e.g. recognize pathogenic fungi by the chitin in their cell walls, triggering disease resistance. Some fungi hide from the immune system by modifying some of the chitin building blocks, converting chitin into chitosan.
Life Sciences - Health - 23.01.2020 
Researchers reconstruct 500 million years of insect evolution
Arthropods, a group of animals including next to insects also spiders or crustaceans, make up the most species-rich and diverse group of animals on Earth, with numerous adaptations that have allowed them to exploit all major ecosystems. However, what genetic mechanisms are responsible for their great evolutionary success' A team of international researchers studied now these species and tracked the evolutionary origin of key adaptations.
Environment - Life Sciences - 17.01.2020
Life Sciences
Results 721 - 740 of 1111.
Coronavirus: University operations limited +++ make use of online services +++ many staff working from home +++ www.tum.de/corona Artificial sugar-binding protein may inhibit cell growth During a viral infection, viruses enter the body and multiply in its cells. Viruses often specifically attach themselves to the sugar structures of the host cells, or present characteristic sugar structures on their surface themselves.
Coronavirus: University operations limited +++ make use of online services +++ many staff working from home Biochemical methods and AI show even the finest capillaries Diseases of the brain are often associated with typical vascular changes. Now, scientists at LMU University Hospital Munich, Helmholtz Zentrum München and at the Technical University of Munich (TUM) have come up with a technique for visualising the structures of all the brain's blood vessels - right down to the finest capillaries - including any pathological changes.
First comprehensive map of the proteome of the model plant Arabidopsis thaliana Plants are essential for life on earth. They provide food for essentially all organisms, oxygen for breathing, and they regulate the climate of the planet. Proteins play a key role in controlling all aspects of life including plants.
Why Individuals Are Not Alike
Neurobiologists studied how brain development influences behavioral differences No 051/2020 from Mar 06, 2020 Neurobiologists at Freie Universität Berlin led by Bassem Hassan, Einstein BIH Visiting Fellow, in collaboration with the group led by Robin Hiesinger at the Department of Biology, Chemistry, and Pharmacy at Freie Universität Berlin, described in a study published in Science why fruit flies display individual behavioral differences despite having the same genotype and being reared in identical environmental conditions.
Neurobiologists studied how brain development influences behavioral differences No 051/2020 from Mar 06, 2020 Neurobiologists at Freie Universität Berlin led by Bassem Hassan, Einstein BIH Visiting Fellow, in collaboration with the group led by Robin Hiesinger at the Department of Biology, Chemistry, and Pharmacy at Freie Universität Berlin, described in a study published in Science why fruit flies display individual behavioral differences despite having the same genotype and being reared in identical environmental conditions.
Biodiversity increases the efficiency of energy use in grasslands Plants obtain their energy from the sun. Other beings rely on eating to survive. Yet how does the energy flow inside ecosystems function and are there differences between ecosystems with many species in comparison to those with few species' Researchers have now examined these questions using a holistic approach by evaluating data gathered through a large-scale biodiversity experiment.
Trusting Our Own Knowledge
What do we know about the topic of climate change and how great is our trust in our own knowledge? An interdisciplinary team of researchers from Heidelberg University has explored this question in a representative study involving around 500 participants. It turned out that those interviewed mainly were uncertain of their own level of knowledge when confronted with false statements.
What do we know about the topic of climate change and how great is our trust in our own knowledge? An interdisciplinary team of researchers from Heidelberg University has explored this question in a representative study involving around 500 participants. It turned out that those interviewed mainly were uncertain of their own level of knowledge when confronted with false statements.
Molecular Motor
How do cells disentangle clumped, and hence non-functional, proteins? A Dutch-German team including researchers from Heidelberg University explored this question. The researchers describe a molecular machine which pulls on exposed loops of the protein chains and extracts them from the protein aggregate.
How do cells disentangle clumped, and hence non-functional, proteins? A Dutch-German team including researchers from Heidelberg University explored this question. The researchers describe a molecular machine which pulls on exposed loops of the protein chains and extracts them from the protein aggregate.
The reproducibility of research results is one of the fundamental quality criteria in science. The demand for transparency of the scientific knowledge process aims to ensure the repeatability of scientific studies or experiments. The project "Opening Reproducible Research" (o2r) of the Institute for Geoinformatics of the University of Münster and the University and State Library of Münster deals with this topic.
Body Temperature Controls Enzyme Activity
A new study at Freie Universität Berlin shows how body temperature regulates certain enzymes and biological processes No 033/2020 from Feb 13, 2020 Researchers from Freie Universität Berlin's Institute of Chemistry and Biochemistry have shown that the activity of a class of enzymes is directly controlled by subtle changes in body temperature.
A new study at Freie Universität Berlin shows how body temperature regulates certain enzymes and biological processes No 033/2020 from Feb 13, 2020 Researchers from Freie Universität Berlin's Institute of Chemistry and Biochemistry have shown that the activity of a class of enzymes is directly controlled by subtle changes in body temperature.
Molecular switch in bone marrow stem cells helps research into inflammatory processes in the brain Life Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.
Transport proteins can switch between microtubule network and actin network Many amphibians and fish are able to change their color in order to better adapt to their environment. Munich-based scientists have now investigated the molecular mechanisms in the cytoskeleton necessary for this and revealed potential evolutionary paths.
While viruses and bacteria regularly manage to infect the human organism, fungi only very rarely succeed. The reason for this is that the human immune system can recognize them very easily because their cells are surrounded by a solid cell wall of chitin and other complex sugars. Chitin is, so to speak, the alarm signal for our immune system, to which it reacts with a whole arsenal of defensive weapons.
Bumble bees prefer a low-fat diet
A bumble bee's diet affects survival and reproductive capabilities Are bees dying of malnourishment? Professor Sara Diana Leonhardt examines the interactions between plants and insects with her work group at the TUM School of Life Sciences Weihenstephan. Using behavioral experiments, her team analyzes how bumble bees evaluate the quality of food sources and how foods of various qualities affect their well-being.
A bumble bee's diet affects survival and reproductive capabilities Are bees dying of malnourishment? Professor Sara Diana Leonhardt examines the interactions between plants and insects with her work group at the TUM School of Life Sciences Weihenstephan. Using behavioral experiments, her team analyzes how bumble bees evaluate the quality of food sources and how foods of various qualities affect their well-being.
Relationship between the economic value of our ecosystems and biodiversity Can the biodiversity of ecosystems be considered a factor of production? A group of researchers under the direction of the Technical University of Munich (TUM) are studying the economic benefits that farmers and foresters can obtain by focusing on several species instead of just one.
Protective protein in the eye lens affects protein oxidation The lens of the human eye comprises a highly concentrated protein solution, which lends the lens its great refractive power. Protective proteins prevent these proteins from clumping together throughout a lifetime. A team of scientists from the Technical University of Munich (TUM) has now uncovered the precise structure of the 'A-crystallin protein and, in the process, discovered an important additional function.
Tree-like Detergent Molecules for Membrane Proteins
Scientists at Freie Universität Berlin and University of Oxford Develop Novel Technique for the Analysis of Membrane Proteins No 017/2020 from Jan 29, 2020 Researchers at Freie Universität Berlin and the University of Oxford developed a method, which enables the gentle release of proteins from membranes.
Scientists at Freie Universität Berlin and University of Oxford Develop Novel Technique for the Analysis of Membrane Proteins No 017/2020 from Jan 29, 2020 Researchers at Freie Universität Berlin and the University of Oxford developed a method, which enables the gentle release of proteins from membranes.
New gene correction therapy for Duchenne muscular dystrophy Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children, leaving them wheelchair-bound before the age of twelve and reducing life expectancy. Researchers at Technical University of Munich (TUM), Ludwig Maximilian University of Munich (LMU) and the German Research Center for Environmental Health (Helmholtz Zentrum München) have developed a gene therapy that may provide permanent relief for those suffering from DMD.
Like animals and humans, plants possess a kind of immune system. It can e.g. recognize pathogenic fungi by the chitin in their cell walls, triggering disease resistance. Some fungi hide from the immune system by modifying some of the chitin building blocks, converting chitin into chitosan.
Arthropods, a group of animals including next to insects also spiders or crustaceans, make up the most species-rich and diverse group of animals on Earth, with numerous adaptations that have allowed them to exploit all major ecosystems. However, what genetic mechanisms are responsible for their great evolutionary success' A team of international researchers studied now these species and tracked the evolutionary origin of key adaptations.
Cyanobacteria produce methane
Cyanobacteria, also known as blue-green algae, are among the most common organisms on Earth and are notorious for forming toxins. A recent study has now shown for the first time that these bacteria produce relevant amounts of methane in oceans, inland waters, and on land. In the course of climate change, increasing blue-green algae blooms will most likely amplify the release of methane into the atmosphere, according to scientists from the Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB) and Heidelberg University of Heidelberg who carried out the research.
Cyanobacteria, also known as blue-green algae, are among the most common organisms on Earth and are notorious for forming toxins. A recent study has now shown for the first time that these bacteria produce relevant amounts of methane in oceans, inland waters, and on land. In the course of climate change, increasing blue-green algae blooms will most likely amplify the release of methane into the atmosphere, according to scientists from the Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB) and Heidelberg University of Heidelberg who carried out the research.
