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Health - Life Sciences - 25.04.2022

Rapid diagnosis instead of a long odyssey
MHH Human Genetics: Whole-genome sequencing to bring the cause of rare diseases in critically ill children to light at an early stage About four million people in Germany suffer from one of the many different rare diseases (SE) - especially seriously ill children who require intensive medical treatment.

Health - Life Sciences - 22.04.2022

A Low-Calorie Diet Alters the Gut Microbiome and Delays Immune Aging
Around 2 billion people worldwide are overweight. Obesity increases the risk of developing high blood pressure, heart attack or type 2 diabetes mellitus and can cause inflammation in the body that weakens the immune system through an accumulation of specific memory T and B cells. This process is called immune senescence, an age-related change in the immune system.

Life Sciences - Health - 22.04.2022

New discoveries about the origin of the brain’s immune system
Important immune cells in the brain's blood vessels do not mature until after birth What gets into the brain and what doesn't is strictly regulated. Researchers at the Faculty of Medicine at the University of Freiburg have now studied phagocytes that coat the blood vessels in the brain and reinforce the blood-brain barrier.

Health - Psychology - 21.04.2022

Protection and Risk: Social Cohesion during Lockdown
The CovSocial Project Analyzes the Mental Health and Social Cohesion of the Citizens of Berlin during the COVID-19 Pandemic In the CovSocial project, scholars and scientists led by Tania Singer from the Social Neuroscience Research Group of the Max Planck Society are investigating how the Covid-19 pandemic has affected the mental health and social cohesion of Berlin citizens during the pandemic years 2020 to 2022.

Life Sciences - Health - 20.04.2022

Enzyme prevents brain activity from getting out of control
Mechanism identified at University of Bonn alters the coupling of nerve cells The brain has the ability to modify the contacts between neurons. Among other things, that is how it prevents brain activity from getting out of control. Researchers from the University Hospital Bonn, together with a team from Australia, have identified a mechanism that plays an important role in this.

Health - Life Sciences - 19.04.2022

New approach against chronic inflammation
Researchers at the University of Bonn are treating mice with so-called "nanobodies" Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies." These nanobodies enabled them to dissolve molecular complexes in tissue that normally activate the immune system.

Health - Life Sciences - 14.04.2022

How mechanical stimuli trigger cellular signalling
International GPCR research collaboration deciphers structure of active receptors Breathing, seeing, hearing - the family of G protein-coupled receptors (GPCRs) is involved in a variety of physiological processes and is also the cause of diverse diseases. As has now been discovered by a team of scientists led by Professor Ines Liebscher from Leipzig University, some members of the GPCR family respond to mechanical stimuli.

Health - Pharmacology - 13.04.2022

COVID-19 therapy: better in combination than alone
How a well-known drug can become a game changer - A joint press release by Charité, the MDC and FU Berlin There is a steadily growing arsenal of drugs for COVID-19. Researchers from Charité - Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität (FU) Berlin have studied the mechanisms of action of antiviral and anti-inflammatory drugs.

Health - 08.04.2022

Insights into the dynamic ultrastructure of the heart
Researchers publish work on the three-dimensional structure of the heart What happens below the cellular level when the heart contracts and relaxes has long been unexplored. Thanks to new ultra-high-resolution electron microscopy techniques, scientists can now watch the heart beating - almost at a molecular level.

Social Sciences - Health - 07.04.2022

Protein boosts height growth in girls
Just seven grams over daily protein intake recommendation can increase height by one centimeter Quite a few young men would like to increase their height. However, a study by nutritionists at the University of Bonn shows that they do not benefit from increased protein intake in terms of their adult height.

Health - Social Sciences - 07.04.2022

Physical intimacy among older couples
A study by Humboldt-Universität zu Berlin and international collaborators reveals: physical intimacy and well-being in old age are closely linked Kissing, touching, or cuddling - older couples who report more physical intimacy in their everyday lives also display better well-being. Yet, men and women experience this differently, and thus experiencing physical intimacy relates to their stress hormone levels in a different way.

Sport - Health - 05.04.2022

Sport improves concentration and quality of life
Physically fit primary school pupils feel better and can concentrate better. They are more likely to make it to higher-level secondary grammar schools than children with less sporting abilities. This has been confirmed for the first time in a study by the Department of Sport and Health Sciences at the Technical University of Munich (TUM).

Life Sciences - Health - 05.04.2022

How Herpesviruses Awaken
Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA. Würzburg researchers show this in the journal "Nature". Eight different herpes viruses are known to date in humans. They all settle down permanently in the body after acute infection.

Health - Pharmacology - 05.04.2022

Researcher wants to stop harmful effect of chemotherapy on heart muscle
EU funds research project to elucidate pathological cardiac remodelling caused by cancer drugs with around 2.5 million euros 04. Heart failure is one of the most common causes of death worldwide. The disease, known in medicine as cardiac insufficiency, affects about four million people in Germany.

Life Sciences - Health - 31.03.2022

University of Cologne wins funding for two new research networks
The University of Cologne has won funding for a new research network. In addition, a proposal for a research network in which the University of Cologne is involved as a partner was successful. The aim of these networks, funded by the Ministry of Culture and Science of the State of North Rhine-Westphalia (MKW NRW), is to create cooperative projects across all types of colleges and universities as well as non-university research institutions to develop new research profiles and to establish strong research partnerships.

Pharmacology - Health - 25.03.2022

Bioactive substance inhibits important receptor
Study shows how bioactive substance inhibits important receptor Study shows how bioactive substance inhibits important receptor Results from the University of Bonn raise hope for new drugs against cancer and brain diseases The A2A receptor regulates how vigorously the innate immune system attacks diseased cells.

Health - Life Sciences - 24.03.2022

There is more to Sars-CoV-2 than meets the eye
The Sars-CoV-2 coronavirus does not only cause infections of the respiratory tract. Other organ systems, such as the nervous system, can also be affected. In fact, Sars-CoV-2 mRNA has been detected in the brain in autopsies of patients who died from Covid-19. There is also growing evidence that coronaviruses can enter the retina of the eye, yet it is unclear which retinal structures are infected by Sars-CoV-2 and whether the retinal pathologies identified in Covid-19 patients are a direct or indirect result of retinal infection.

Health - Life Sciences - 22.03.2022

How sugar promotes inflammation
03/22/2022 Excessive sugar consumption can promote inflammatory processes in the body and facilitate the development of autoimmune diseases. A research team at the University of Würzburg has now deciphered new details of these processes. People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease.

Life Sciences - Health - 22.03.2022

New CRISPR Element Regulates Viral Defense
03/22/2022 Researchers from Würzburg, Freiburg and Leipzig discover a mechanism for prioritizing the immune response in bacteria. What tasks need to be done today, and which is the most urgent? People have to constantly set priorities in their daily life. Bacteria are no different: They too must prioritize when combating viruses with CRISPR.

Health - Pharmacology - 22.03.2022

The right diet can safeguard against acute kidney injury
A research team led by Professor Dr Roman-Ulrich Müller has established that four out of six different nutritional strategies prevent acute kidney injury in the mouse model. Furthermore, the team identified a potential mechanism protecting the organs in their interdisciplinary, translational study. This is the first step towards transferring the results from bench to bedside.