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Life Sciences - Health - 09.08.2024
Alzheimer's disease: It's not only neurons
Alzheimer’s disease: It’s not only neurons
Memory loss, confusion, speech problems - Alzheimer's disease is the most common cause of dementia, affecting about 35 million people worldwide, and the number is growing. The protein amyloid beta, which occurs naturally in the brain, plays a central role in the disease: It accumulates in patients in insoluble clumps that form plaques between neurons in the brain, damaging them.

Life Sciences - Health - 08.08.2024
Successful fasting needs spermidine
Successful fasting needs spermidine
Prerequisite for protective effects of fasting is an increase in the concentration of the endogenous substance spermidine in the organism / international study involving the team of Stephan Sigrist from Freie Universität According to the results of an international study involving the Freie Universität Berlin, fasting can prolong life and increase the health span.

Life Sciences - Health - 08.08.2024
Successful Fasting Requires Spermidine
Successful Fasting Requires Spermidine
The protective effects of fasting depend on an increase in the concentration of spermidine, according to an international study involving a team led by Professor Stephan Sigrist from Freie Universität Berlin According to the findings of an international study, fasting can extend people's lifespan and increase overall health.

Health - Life Sciences - 05.08.2024
Study sheds new light on how our immune system works
Study sheds new light on how our immune system works
Mast cells trap and use living neutrophils during allergic reactions Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation.

Health - Life Sciences - 02.08.2024
Allergy cells' hidden secret
Allergy cells’ hidden secret
Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation. Now, researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the University of Münster have discovered a hidden talent of mast cells: they can capture and use another type of immune cell called neutrophils.

Life Sciences - Health - 31.07.2024
Tiny tubes in the brain
Tiny tubes in the brain
Immune cells in the brain form bridges to nerve cells and protect against neurodegenerative diseases When nerve cells in the brain die, diseases such as Alzheimer's and Parkinson's develop. To protect these cells, there are immune cells in the brain known as microglia. A study has now shown that microglia form tiny tubes, so-called -tunnelling nanotubes-, and thus connect directly to the nerve cells.

Health - Life Sciences - 31.07.2024
Keeping skin healthy: New method provides molecular portrait of sebum production
Keeping skin healthy: New method provides molecular portrait of sebum production
In a collaborative project between the Faculty of Veterinary Medicine and the Interdisciplinary Centre for Bioinformatics (IZBI) at Leipzig University, changes in gene expression in sebaceous glands have been spatially mapped for the first time. The study documents at high resolution changes in gene expression in the course of sebum synthesis and identifies new candidates for the modulation of sebum production.

Health - 30.07.2024
Cell atlas of regenerating liver
Cell atlas of regenerating liver
The liver has a remarkable ability to regenerate. This property is crucial for maintaining organ function and recovery after injury or surgery. Scientists from the University of Leipzig Medical Center, the Max Planck Institute for Evolutionary Anthropology, TU Dresden and ETH Zurich have used clinical samples to investigate how cell types in the liver change before and after regeneration.

Health - Innovation - 25.07.2024
Little Trust in Dr. ChatGPT
People trust medical advice less if they suspect that an artificial intelligence is involved in its creation. This is the key finding of a study by psychologists from the University of Würzburg. People used to ask Dr. Google if they wanted to know whether their symptoms indicate a mild stomach upset or terminal cancer; today, they are increasingly turning to ChatGPT.

Health - Life Sciences - 24.07.2024
Large genetic study on severe COVID-19
Large genetic study on severe COVID-19
Bonn researchers confirm three other genes for increased risk in addition to the known TLR7 gene Whether or not a person becomes seriously ill with COVID-19 depends, among other things, on genetic factors. With this in mind, researchers from the University Hospital Bonn (UKB) and the University of Bonn, in cooperation with other research teams from Germany, the Netherlands, Spain and Italy, investigated a particularly large group of affected individuals.

Life Sciences - Health - 18.07.2024
Analysing internal world models of humans, animals and AI
Analysing internal world models of humans, animals and AI
Freiburg researchers develop new formal description of internal world models, thereby enabling interdisciplinary research A team of scientists led by Ilka Diester , Professor of Optophysiology and spokesperson of the BrainLinks-BrainTools research centre at the University of Freiburg, has developed a formal description of internal world models and published it in the journal Neuron .

Life Sciences - Health - 17.07.2024
Addition to the CRISPR Toolbox: Teaching Gene Scissors to Detect RNA
Addition to the CRISPR Toolbox: Teaching Gene Scissors to Detect RNA
A team at the Helmholtz Centre for Infection Research in Würzburg, Germany, led by RNA expert Chase Beisel, has developed a new technology for the precise detection of RNA using DNA-cutting Cas12 nucleases. CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

Health - Physics - 15.07.2024
New insights into molecular mechanisms of cholera infection
New insights into molecular mechanisms of cholera infection
Researchers investigate the strong interaction of cholera toxin with a key ganglioside on the surface of intestinal cells Cholera infections caused by Vibrio cholerae bacteria can be life-threatening and the trigger is the cholera toxin produced by the bacteria. It binds to the surface of intestinal cells - more precisely, to certain "sugar lipids" (GM1 gangliosides, GM1) on the cell surfaces.

Health - 15.07.2024
Lifestyle changes support reduction in the risk of dementia
There are currently around 1.8 million people living with dementia in Germany. Due to increased life expectancy, the proportion will continue to grow: based on data from the Federal Statistical Office, experts expect up to two million cases in 2033. For the first time, an intervention study was carried out to prevent mental decline in older GP patients.

Health - Life Sciences - 10.07.2024
Why aortic aneurysms occur at the vascular arch or in the abdominal section
Why aortic aneurysms occur at the vascular arch or in the abdominal section
The usual sites where vascular bulges form are predestined for this from the outset, even in healthy people. This is shown by a study conducted by the Bochum and Bonn medical departments. If a vascular aneurysm bursts in the aorta, it poses an acute danger to life. These so-called aortic aneurysms typically form in the same places on the large blood vessel: either on the upper arch or in the abdominal cavity.

Health - 10.07.2024
Early detection of vision loss in age-related macular degeneration (AMD)
Early detection of vision loss in age-related macular degeneration (AMD)
New research by the University Hospital Bonn (UKB) in cooperation with the University of Bonn has shown for the first time that certain early changes in patients with age-related macular degeneration (AMD) can lead to a measurable local loss of vision. This discovery could help to improve the treatment and monitoring of this eye disease in older patients, which otherwise slowly leads to central blindness, and to test new therapies.

Life Sciences - Health - 09.07.2024
Unique characteristics of previously unexplored protein discovered
Freiburg-Prague research collaboration achieves scientific breakthrough in understanding cell division.

Health - 08.07.2024
New pathway in immune defense discovered
New pathway in immune defense discovered
Bonn researchers decode the interaction of monocytes and platelets in human blood Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have now discovered that platelets, also known as thrombocytes, communicate with monocytes and increase their inflammatory capacity.

Health - Pharmacology - 08.07.2024
Active Plant Substance Reduces Pulmonary Hypertension
Active Plant Substance Reduces Pulmonary Hypertension
A substance derived from the plant Ardisia crenata works in a different way than existing drugs. And in doing so, it is highly effective. Pulmonary hypertension is a very serious disease that leads to heart failure and death in many patients. Searching for new treatment options, a team headed by Professor Daniela Wenzel and Alexander Seidinger from the Department of Systems Physiology at Ruhr University Bochum, Germany, tested the plant substance FR900359 - referred to as FR by the researchers.

Health - Life Sciences - 05.07.2024
Why Aortic Aneurysms Form at the Arch or in the Abdominal Segment
The sites where vascular aneurysms typically form have a predilection from the outset, even in healthy people. This is shown by a study conducted by medical researchers from Bochum and Bonn. A vascular dilatation in the aorta can be life-threatening if it bursts. These so-called aortic aneurysms typically form in the same sites of the large blood vessel: either on the upper arch or in the abdominal cavity.