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News from the Lab (news.myScience.ch)

  • News from the Lab’ is a selection of scientific works that are significant or interesting for a broad readership. 
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Health - Pharmacology - 30.07.2021
Combination vaccines against Covid-19 tested
Immune response stronger than after two doses of AstraZeneca vaccine People under the age of 60 who initially received a vaccine from AstraZeneca should be given an mRNA vaccine at their second appointment. This is recommended by the German Standing Committee on Vaccination. However, up until now, there were no data available to indicate to what extent the human organism would react to such a combined vaccination and start to form antibodies.

Health - Pharmacology - 30.07.2021
Mix-and-match vaccines against Covid-19 tested
Immune response stronger than after two doses of AstraZeneca vaccine People under the age of 60 who initially received a vaccine from AstraZeneca should be given an mRNA vaccine at their second appointment. This is recommended by the German Standing Committee on Vaccination. However, up until now, there were no data available to indicate to what extent the human organism would react to such a mix-and-match vaccination and start to form antibodies.

Health - Life Sciences - 30.07.2021
New strategy against sepsis
New strategy against sepsis
Some cases of bloodstream infections are mild, but many have a fatal outcome - the reasons for these differences have remained in the dark despite decades of research. Researchers from the Cluster of Excellence "Controlling Microbes to Fight Infections" (CMFI), the Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT) at the University of Tübingen and the German Center for Infection Research (DZIF) have now discovered a possible cause and on this basis developed a new experimental strategy to combat bacterial sepsis.

Life Sciences - Health - 29.07.2021
Energy for undisturbed rest
Energy for undisturbed rest
07/29/2021 In the fruit fly Drosophila, a hormone helps to balance rest and activity. This is shown by a new study of a research team led by the University of Würzburg. Might humans have a hormone with comparable function? Searching for food, eating, resting: in rough terms, this is the rhythm of life that many animals follow.

Life Sciences - Health - 28.07.2021
New regulators of the aging process
New regulators of the aging process
The attachment of the small protein ubiquitin to other proteins (ubiquitination) regulates numerous biological processes, including signal transduction and metabolism / Scientists at the University of Cologne discover the link to aging and longevity / Publication in 'Nature'. Scientists have discovered that the protein ubiquitin plays an important role in the regulation of the aging process.

Materials Science - Health - 27.07.2021
First synthetic tissue model developed in which blood vessels can grow
First synthetic tissue model developed in which blood vessels can grow
Researchers investigate which material properties support vessel formation / Study published in the journal "Nature Communications" Using lab-created tissue to heal or replace damaged organs is one of the great visions for the future of medicine. Synthetic materials could be suitable as scaffolding for tissue because, unlike natural tissues, they remain stable in the organism long enough for the body to form new natural structures.

Health - Life Sciences - 27.07.2021
Model developed to predict the effect of antibody treatment in HIV infection
The dosage of broadly neutralizing antibodies determines the ability for virus replication / findings can contribute to design HIV therapy that can durably suppress the virus A Cologne-based research collaboration has found a way to predict the effect of broadly neutralizing antibodies (bnAbs) on the growth rate of HIV-1.

Health - Life Sciences - 19.07.2021
Cancer development is influenced by tissue type
Cancer development is influenced by tissue type
Why identical mutations cause different types of cancer Why do alterations of certain genes cause cancer only in specific organs of the human body? Scientists have now demonstrated that cells originating from different organs are differentially susceptible to activating mutations in cancer drivers: The same mutation in precursor cells of the pancreas or the bile duct leads to fundamental different outcomes.

Life Sciences - Health - 08.07.2021
Stiffness of skin tissue determines the renewal capacity of stem cells
Stiffness of skin tissue determines the renewal capacity of stem cells
Old and young skin stem cells are both capable of renewing the skin and its hair follicles. A slower renewal turnover of aged skin and its hair follicles may be caused by the decreased elasticity of skin tissues surrounding the stem cells / New insights into the causes of aging published in 'Nature Cell Biology' An international team of researchers from the Universities of Cologne and Helsinki have discovered that the ability of stem cells to proliferate and renew organs is regulated by the stiffness of the surrounding tissue.

Health - Life Sciences - 07.07.2021
MHH fills important gap in lung research
MHH fills important gap in lung research
For the first time, a team of scientists clearly demonstrates the existence of lipofibroblasts in human luectron microscope In medical research, animal models are used to clarify the development of diseases and to develop suitable therapies. In order to be able to transfer the results to humans, however, it must be ensured that the cell types and molecular signalling pathways studied in detail actually occur in our bodies.

Health - Life Sciences - 06.07.2021
Anti-tumor agent from the intestine
Anti-tumor agent from the intestine
Certain metabolites of bacteria from the intestine make immune cells more aggressive as a new study conducted by scientists from Würzburg and Marburg reveals. The findings could help improve cancer therapies. It is believed to be involved in the development of chronic inflammatory intestinal diseases, to trigger diabetes, to be responsible for obesity, even neurological diseases such as multiple sclerosis and Parkinson's could have their causes here - not to mention depressions and autistic disorders.

Social Sciences - Health - 30.06.2021
Modernization makes older adults feel rushed, too
New international study on time perception among older adults Rapid societal changes can leave us feeling more rushed and pressured for time - and older adults are no exception, new research finds, led by Weill Cornell Medicine with participation of researchers of Humboldt University.

Life Sciences - Health - 28.06.2021
Protein balance in the reproductive system can prevent disease
Protein balance in the reproductive system can prevent disease
Scientists from the University of Cologne found that the balance status of proteins (protein homeostasis) of germline cells influences protein aggregation in other tissues by long-distance signaling Publication in 'Science Advances' A recent study shows that a healthy reproductive system can prevent disease-related protein accumulation in distant tissues, such as neurons, and alteration of mitochondria - the power plants of cells.

Health - Life Sciences - 24.06.2021
Versatile and reliable SARS-CoV-2 antibody assay
Versatile and reliable SARS-CoV-2 antibody assay
Automated microarray rapid test for detecting SARS-CoV-2 antibodies During the continued progression of the Corona pandemic, rapid, inexpensive, and reliable tests will become increasingly important to determine whether people have the associated antibodies - either through infection or vaccination. Researchers at the Technical University of Munich (TUM) have now developed such a rapid antibody test.

Life Sciences - Health - 24.06.2021
New Findings on Body Axis Formation
New Findings on Body Axis Formation
Heidelberg researchers discover an enzyme that prevents the formation of multiple heads and axes in the freshwater polyp Hydra In the animal kingdom, specific growth factors control body axis development. These signalling molecules are produced by a small group of cells at one end of the embryo to be distributed in a graded fashion toward the opposite pole.

Life Sciences - Health - 23.06.2021
Rare Genetic Defect Replicated in Fish Model
A rare genetic defect that affects the so-called ALG2 gene can cause serious metabolic diseases in humans. It does so through the defective formation of proteins and sugar molecules. Until now, its rareness and complexity made it difficult to study this congenital glycosylation disorder.

Life Sciences - Health - 22.06.2021
Animal health through genomics
Animal health through genomics
Feasibility study: Preventing diseases through genome analysis and genome scissors Why are some animals more susceptible to diseases than others? Scientists at the Technical University of Munich (TUM) investigated this in more detail. They found genetic differences in livestock species that make individual animals less susceptible to certain diseases.

Health - 22.06.2021
How satiation can be controlled
How satiation can be controlled
Secretin hormone induces satiation by activating brown fat Researchers at the Technical University of Munich (TUM) and the Finnish research institute Turku PET Centre have discovered a new mechanism controlling satiation. According to the recently published study, the hormone secretin induces satiation by activating brown adipose tissue.

Chemistry - Health - 07.06.2021
Clever biomolecular labelling enables identification of immune cells
Clever biomolecular labelling enables identification of immune cells
Research team led by the University of Göttingen develops new strategy for labelling peptides Biomolecules regulate the biological functions inside every living cell. If scientists can understand the molecular mechanisms of such functions, then it is possible to detect severe dysfunction which can lead to illness.

Health - Sport - 02.06.2021
'Corona fuels a different pandemic'
’Corona fuels a different pandemic’
Survey on diet and exercise since the start of the corona pandemic presented How has the corona pandemic affected the dietary and exercise behavior and thus the weight of adults? Researchers at the Technical University of Munich (TUM) have investigated this question and found that about 40 percent of those surveyed have gained weight since the start of the pandemic and that slightly more than half of those surveyed have exercised less than they did before the corona crisis.
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