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News from the Lab (news.myScience.ch)

  • News from the Lab’ is a selection of scientific works that are significant or interesting for a broad readership. 
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Pharmacology



Results 1 - 20 of 39.


Health - Pharmacology - 17.12.2020
Breathing rate predicts therapeutic benefits for heart patients
Discovering a forgotten biosignal Conditions causing arrhythmia are among the most common cardiac conditions. A study headed by Prof. Georg Schmidt of the Technical University of Munich (TUM) has demonstrated for the first time that the nocturnal respiratory rate can help with an important prediction: It is an indicator of whether a defibrillator will help to extend the life of patients with arrhythmia.

Health - Pharmacology - 02.11.2020
How the immune system remembers viruses
How the immune system remembers viruses
Immune response: memory T cells are formed earlier than previously thought For a person to acquire immunity to a disease, T cells must develop into memory cells after contact with the pathogen. Until now, the number of cells that do this was believed to depend above all on the magnitude of the initial immune response.

Pharmacology - Health - 23.10.2020
Is Antimicrobial Resistance Evolution Accelerating?
A team of researchers from Freie Universität Berlin and ETH Zurich studied if antifungal and antibiotic resistance emerge faster than in the past No 199/2020 from Oct 23, 2020 Scientists from Freie Universität Berlin and Eidgenössische Technische Hochschule Zürich (ETH Zurich) investigated how long it takes for resistance to emerge after the introduction of a new antifungal or antibiotic.

Health - Pharmacology - 13.10.2020
Safely on the way to effective tumour cell killing
Safely on the way to effective tumour cell killing
Scientists at the University of Göttingen develop drug for antibody tumour therapy Chemists at the University of Göttingen have developed new cytotoxic drugs which could revolutionise antibody-based tumour therapy approaches. The research team succeeded in modifying the natural product Duocarmycin into -prodrug- formats - which means that it only develops its effect once inside the tumour cell, thus reducing the likelihood of potential side effects on passage through the body.

Pharmacology - Health - 25.09.2020
Secure nano-carrier delivers medications directly to cells
Secure nano-carrier delivers medications directly to cells
Nanoparticles with synthetic DNA can control release of drugs Medications often have unwanted side-effects. One reason is that they reach not only the unhealthy cells for which they are intended, but also reach and have an impact on healthy cells. Researchers at the Technical University of Munich (TUM), working together with the KTH Royal Institute of Technology in Stockholm, have developed a stable nano-carrier for medications.

Pharmacology - Life Sciences - 02.09.2020
Finding cortisone alternatives with fewer side effects
Finding cortisone alternatives with fewer side effects
DNA binding is essential for effectiveness of steroids Many people use cortisone of a regular basis. It is used for treating rheumatism, asthma, multiple sclerosis, or even COVID-19. Steroidal medication such as cortisone is highly effective but also possesses severe side effects. Henriette Uhlenhaut, professor at Technical University of Munich (TUM), and her team are examining the beneficial effects of cortisone in order to lay the groundwork for the development of similar drugs with fewer side effects.

Chemistry - Pharmacology - 16.07.2020
Researchers solve a long-standing problem in organic chemistry
Researchers solve a long-standing problem in organic chemistry
Chemists at the University of Münster develop a bioinspired strategy for the controlled synthesis of polyenes / Study published in "Science" They occur in nature, are reactive and play a role in many biological processes: polyenes. It is no wonder that chemists have for a long time been interested in efficiently constructing these compounds - not least in order to be able to use them for future biomedical applications.

Health - Pharmacology - 23.06.2020
The tricks of the immune system
The tricks of the immune system
How the T-cell response changes in chronic virus infections "The Covid-19 pandemic clearly demonstrates the importance of understanding how the immune system reacts to virus infections," says Dr. Kilian Schober. Together with an interdisciplinary team of researchers from Medicine, Biology and Bioinformatics, he is investigating how important agents in the body's immune system known as T lymphocytes or T cells react when a virus invades the organism and how the immune response changes when the infection becomes chronic.

Pharmacology - Health - 05.06.2020
A newly discovered disease may lead to better treatment of cystic fibrosis
A newly discovered disease may lead to better treatment of cystic fibrosis
Cystic fibrosis is the most frequent severe inherited disorder worldwide. Every year, hundreds of families are confronted with this diagnosis - and to date, there is no cure for this disease that mainly affects the respiratory system. Besides supportive treatments, a lung transplant is often the only option to save a patient's live.

Health - Pharmacology - 03.06.2020
Remdesivir effective against Covid-19 even after short treatment periods
Remdesivir effective against Covid-19 even after short treatment periods
Comparable clinical results after five and ten days of treatment In an international study, scientists from eight countries have investigated the use of the medication Remdesivir in the treatment of Covid-19. One result of the study, which included the participation of the Technical University of Munich's university hospital TUM Klinikum rechts der Isar: The changes in the clinical condition of patients treated for five days were comparable to the changes in patients treated for a period of ten days.

Pharmacology - Life Sciences - 01.05.2020
An Alternative for Antibiotics
International Team of Researchers Investigates Antibacterial Effects of Antimicrobial Peptides No 073/2020 from May 01, 2020 Scientists at Cornell University, Georgetown University, and Freie Universität Berlin have analyzed and summarized to what extent antimicrobial peptides, such as those found in plants and animals, can be used as an alternative to conventional antibiotics.

Pharmacology - Computer Science - 27.04.2020
Researchers develop software for drug repurposing
Researchers develop software for drug repurposing
Currently, the corona pandemic is dominating the entire social life in Germany and in many other parts of the world. We are working flat out in order to better help the more than one hundred thousand seriously ill people in hospitals. One promising approach to extending current treatment methods is to use existing and approved drugs to combat the virus.

Health - Pharmacology - 24.04.2020
Parasite larvae could help fight allergies
Our immune system protects us against pathogens. However, an excessive immune reaction can trigger allergies or chronic asthma. Scientists at the Technical University of Munich (TUM) and Helmholtz Zentrum München have discovered an active ingredient taken from the larvae of a worm parasite that could help diminish immune reactions.

Health - Pharmacology - 21.04.2020
In-ear sensors to help in fight against COVID-19
In-ear sensors to help in fight against COVID-19
A team at the Technical University of Munich (TUM) plans to use high-tech biometric sensors for 24-hour monitoring of COVID-19 patients in home isolation. The goal of the study is to find out whether rapid treatment in response to deteriorating vital signs can improve the chance of survival and ease the workload of intensive care units.

Health - Pharmacology - 08.04.2020
New Alliance in the Fight Against Coronavirus and COVID-19
Researchers at Heidelberg University have formed an alliance - the fightCOVID @ Heidelberg research and development task force - with the aim to curb the coronavirus pandemic. To this end, scientists of the two Medical Faculties and the Heidelberg and Mannheim University Hospitals, the BioQuant centre, the Center for Molecular Biology and the Central Institute of Mental Health in Mannheim have joined forces with colleagues from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory (EMBL) in Heidelberg.

Pharmacology - Health - 26.03.2020
Medications against coronavirus in trial
Medications against coronavirus in trial
Clinical trials on Covid-19 at university hospital TUM Klinikum rechts der Isar The university hospital is participating in studies on new medications for people suffering from Covid-19. As part of a clinical study, patients can be treated with medications that are still under development. 50 patients infected with the novel Coronavirus are currently being treated at the university hospital TUM Klinikum rechts der Isar.

Pharmacology - Health - 04.02.2020
Hepatitis B: New therapeutic approach
Hepatitis B: New therapeutic approach
Therapeutic vaccination may help to cure chronic hepatitis B infection Researchers at Technical University of Munich (TUM), Helmholtz Zentrum München and the German Center for Infection Research (DZIF) have developed a novel therapeutic approach to cure chronic hepatitis B. The scientists found that the large amount of hepatitis B virus proteins expressed in the liver prevents the body's immune system to defeat the virus.

Health - Pharmacology - 04.02.2020
What can be done to combat the third leading cause of death worldwide?
Freie Universität Berlin participates in international research project to develop new therapies against antibiotic-resistant pathogens of pneumonia / Funded with 10 million euros from the European Union No 025/2020 from Feb 04, 2020 Scientists from eleven European research institutions, including the Institute of Pharmacy at Freie Universität Berlin, are jointly looking for new ways to combat antibiotic-resistant pathogens.

Health - Pharmacology - 18.12.2019
Using AI to understand the spread of cancer
Using AI to understand the spread of cancer
New deep learning algorithm DeepMACT detects the smallest metastases Researchers at the Technical University of Munich (TUM), the Helmholtz Zentrum München and the LMU Munich have developed a new algorithm that automatically detects metastases. The new technology uses artificial intelligence (AI) and even finds single disseminated cancer cells in the body of mice.

Pharmacology - Health - 16.12.2019
From cancer medication to antibiotic
From cancer medication to antibiotic
Modified cancer drug effective against multi-resistant bacteria Antibiotic-resistant bacteria are increasingly the source of deadly infections. A team of scientists from the Technical University of Munich (TUM) and the Helmholtz Center for Infection Research (HZI) in Braunschweig have now modified an approved cancer drug to develop an active agent against multidrug-resistant pathogens.

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