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News from the Lab (news.myScience.ch)

  • News from the Lab’ is a selection of scientific works that are significant or interesting for a broad readership. 
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Pharmacology



Results 1 - 20 of 32.


Health - Pharmacology - 23.06.2020
The tricks of the immune system
The tricks of the immune system
How the T-cell response changes in chronic virus infections "The Covid-19 pandemic clearly demonstrates the importance of understanding how the immune system reacts to virus infections," says Dr. Kilian Schober. Together with an interdisciplinary team of researchers from Medicine, Biology and Bioinformatics, he is investigating how important agents in the body's immune system known as T lymphocytes or T cells react when a virus invades the organism and how the immune response changes when the infection becomes chronic.

Pharmacology - Health - 05.06.2020
A newly discovered disease may lead to better treatment of cystic fibrosis
A newly discovered disease may lead to better treatment of cystic fibrosis
Cystic fibrosis is the most frequent severe inherited disorder worldwide. Every year, hundreds of families are confronted with this diagnosis - and to date, there is no cure for this disease that mainly affects the respiratory system. Besides supportive treatments, a lung transplant is often the only option to save a patient's live.

Health - Pharmacology - 03.06.2020
Remdesivir effective against Covid-19 even after short treatment periods
Remdesivir effective against Covid-19 even after short treatment periods
Comparable clinical results after five and ten days of treatment In an international study, scientists from eight countries have investigated the use of the medication Remdesivir in the treatment of Covid-19. One result of the study, which included the participation of the Technical University of Munich's university hospital TUM Klinikum rechts der Isar: The changes in the clinical condition of patients treated for five days were comparable to the changes in patients treated for a period of ten days.

Pharmacology - Life Sciences - 01.05.2020
An Alternative for Antibiotics
International Team of Researchers Investigates Antibacterial Effects of Antimicrobial Peptides No 073/2020 from May 01, 2020 Scientists at Cornell University, Georgetown University, and Freie Universität Berlin have analyzed and summarized to what extent antimicrobial peptides, such as those found in plants and animals, can be used as an alternative to conventional antibiotics.

Pharmacology - Computer Science - 27.04.2020
Researchers develop software for drug repurposing
Researchers develop software for drug repurposing
Currently, the corona pandemic is dominating the entire social life in Germany and in many other parts of the world. We are working flat out in order to better help the more than one hundred thousand seriously ill people in hospitals. One promising approach to extending current treatment methods is to use existing and approved drugs to combat the virus.

Health - Pharmacology - 24.04.2020
Parasite larvae could help fight allergies
Our immune system protects us against pathogens. However, an excessive immune reaction can trigger allergies or chronic asthma. Scientists at the Technical University of Munich (TUM) and Helmholtz Zentrum München have discovered an active ingredient taken from the larvae of a worm parasite that could help diminish immune reactions.

Health - Pharmacology - 21.04.2020
In-ear sensors to help in fight against COVID-19
In-ear sensors to help in fight against COVID-19
A team at the Technical University of Munich (TUM) plans to use high-tech biometric sensors for 24-hour monitoring of COVID-19 patients in home isolation. The goal of the study is to find out whether rapid treatment in response to deteriorating vital signs can improve the chance of survival and ease the workload of intensive care units.

Health - Pharmacology - 08.04.2020
New Alliance in the Fight Against Coronavirus and COVID-19
Researchers at Heidelberg University have formed an alliance - the fightCOVID @ Heidelberg research and development task force - with the aim to curb the coronavirus pandemic. To this end, scientists of the two Medical Faculties and the Heidelberg and Mannheim University Hospitals, the BioQuant centre, the Center for Molecular Biology and the Central Institute of Mental Health in Mannheim have joined forces with colleagues from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory (EMBL) in Heidelberg.

Pharmacology - Health - 26.03.2020
Medications against coronavirus in trial
Medications against coronavirus in trial
Clinical trials on Covid-19 at university hospital TUM Klinikum rechts der Isar The university hospital is participating in studies on new medications for people suffering from Covid-19. As part of a clinical study, patients can be treated with medications that are still under development. 50 patients infected with the novel Coronavirus are currently being treated at the university hospital TUM Klinikum rechts der Isar.

Pharmacology - Health - 04.02.2020
Hepatitis B: New therapeutic approach
Hepatitis B: New therapeutic approach
Therapeutic vaccination may help to cure chronic hepatitis B infection Researchers at Technical University of Munich (TUM), Helmholtz Zentrum München and the German Center for Infection Research (DZIF) have developed a novel therapeutic approach to cure chronic hepatitis B. The scientists found that the large amount of hepatitis B virus proteins expressed in the liver prevents the body's immune system to defeat the virus.

Health - Pharmacology - 04.02.2020
What can be done to combat the third leading cause of death worldwide?
Freie Universität Berlin participates in international research project to develop new therapies against antibiotic-resistant pathogens of pneumonia / Funded with 10 million euros from the European Union No 025/2020 from Feb 04, 2020 Scientists from eleven European research institutions, including the Institute of Pharmacy at Freie Universität Berlin, are jointly looking for new ways to combat antibiotic-resistant pathogens.

Health - Pharmacology - 18.12.2019
Using AI to understand the spread of cancer
Using AI to understand the spread of cancer
New deep learning algorithm DeepMACT detects the smallest metastases Researchers at the Technical University of Munich (TUM), the Helmholtz Zentrum München and the LMU Munich have developed a new algorithm that automatically detects metastases. The new technology uses artificial intelligence (AI) and even finds single disseminated cancer cells in the body of mice.

Pharmacology - Health - 16.12.2019
From cancer medication to antibiotic
From cancer medication to antibiotic
Modified cancer drug effective against multi-resistant bacteria Antibiotic-resistant bacteria are increasingly the source of deadly infections. A team of scientists from the Technical University of Munich (TUM) and the Helmholtz Center for Infection Research (HZI) in Braunschweig have now modified an approved cancer drug to develop an active agent against multidrug-resistant pathogens.

Chemistry - Pharmacology - 03.12.2019
Two chiral catalysts working hand in hand
Two chiral catalysts working hand in hand
Chemists at Münster University develop a synthetic method providing access to different stereoisomers of a molecule / Study published in 'Nature Catalysis' Just as our left hand is not superposable to our right hand, the mirror image of certain molecules cannot be overlapped onto it, even when turned or twisted.

Pharmacology - Health - 14.10.2019
Inactive receptor renders immunotherapies ineffective
Inactive receptor renders immunotherapies ineffective
The aim of immunotherapies is to enable the immune system once again to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one third of patients. Based on analysis of human tissue samples, a team from the Technical University of Munich (TUM) has now discovered one reason why this is so: an inactive receptor in cancer cells prevents the drugs from reactivating the immune system.

Pharmacology - Life Sciences - 07.10.2019
How Plants React to Fungi
How Plants React to Fungi
Using special receptors, plants recognize when they are at risk of fungal infection. This new finding could help cultivate resistant crops and reduce pesticide usage. Plants are under constant pressure from fungi and other microorganisms. The air is full of fungal spores, which attach themselves to plant leaves and germinate, especially in warm and humid weather.

Pharmacology - Health - 02.10.2019
New approach to pain treatment in diseases of the pancreas
New approach to pain treatment in diseases of the pancreas
One of the worst symptoms associated with inflammation or cancer of the pancreas is severe chronic pain. Pancreatic pain is difficult to treat, because many painkillers prove ineffective in pancreatic patients. In a recent study, a team at the Technical University of Munich (TUM) discovered the cause of this phenomenon for the first time: a particular neuroenzyme in the body is present in the nerves of the organ in high concentrations.

Pharmacology - Health - 12.09.2019
Asthma Medication as Doping Agent?
Prospective Students Students and Doctorate Alumni and Supporters Continuing Education Study by Ulm University Medical Center examines effect of asthma medication on athletic performance / Cooperation with Freie Universität Berlin and German Sport University Cologne No 265/2019 from Sep 12, 2019 A new study conducted this year by the Sports and Rehabilitation Medicine Unit at Ulm University Medical Center is examining how asthma medications affect athletic performance in professional athletes.

Health - Pharmacology - 11.07.2019
Successful’T cell engineering with gene scissors
There are two forms of T cell therapy: either a recipient receives cells from a donor, or the recipient's own T cells are removed, genetically reprogrammed in a laboratory and unleashed against an infection or tumor in the body. While the first method has proven to be successful in clinical models, reprogramming T cells is still beset with problems.

Chemistry - Pharmacology - 02.07.2019
Chemists give chance a helping hand
Chemists give chance a helping hand
Whether they are synthetic materials such as PET and Teflon, medicines or flavourings, life without synthetically produced compounds is barely conceivable in our everyday lives today. The chemical industry depends on efficient, long-term methods of producing synthetically derived molecules. For this purpose, chemists often use catalysts, i.e. additives with which they can facilitate and control chemical reactions.

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