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Health - Life Sciences - 19.01.2024
Antibiotics highjack bacterial immunity
Antibiotics highjack bacterial immunity
Bacteria have an immune system that protects them against viruses known as bacteriophages. A research team from the Universities of and Würzburg has now shown how this immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae . The immune system is the reason why this bacterium is particularly sensitive to one of the oldest known classes of antibiotics - the antifolates.

Life Sciences - Health - 18.01.2024
Exploding kamikaze bacteria
Exploding kamikaze bacteria
"Soldier" bacteria filled with toxins sacrifice themselves for the benefit of their conspecifics, giving them pathogenic properties For their invasion pathogenic bacteria target the host's defense mechanisms and vital cell functions with toxins. Before these deadly substances can attack host cells, bacteria must first export them from their production site - the cytoplasm - using dedicated secretion systems.

Health - Life Sciences - 17.01.2024
Scientific Year Environment and Health: Research for a healthy life
Scientific Year Environment and Health: Research for a healthy life
Technologies that pave the way for our well-being - in numerous interdisciplinary research projects, scientists at TU Ilmenau are developing innovative technological solutions that improve our quality of life. At the kick-off of the new Scientific Year Environment and Health, researchers spoke about their pioneering work.

Health - Life Sciences - 16.01.2024
Special RNA suppresses the formation of breast cancer cells
Special RNA suppresses the formation of breast cancer cells
Breast cancer is the most common cancer in women. The development of breast cancer often originates from epithelial cells in the mammary gland - the very cells that specialise in milk production during and after pregnancy. A team of researchers from Friedrich Schiller University Jena , the university in Shenzhen (China) and Jena University Hospital has taken a closer look at this specialisation process and deciphered a molecular mechanism that also appears to play an important role in cancer development.

Life Sciences - 15.01.2024
Tracking Molecules at Turbo Speed
Tracking Molecules at Turbo Speed
University of Bonn researchers devise method to speed up observations of high-throughput microbiological process Being able to observe micro-organisms and their cellular components is key to understanding fundamental processes that go on inside cells-and thus potentially developing new medical treatments.

Health - Life Sciences - 12.01.2024
Lupus trigger discovered
Lupus trigger discovered
Researchers were able to trace a form of the autoimmune disease lupus back to a single mutation   Sometimes a single mutation in our genetic make-up is enough to cause disease. This is also the case with the autoimmune disease lupus. Lupus causes severe inflammation throughout the body and can have a serious impact on the lives of those affected.

Life Sciences - 12.01.2024
How Fruit Flies Smell CO2
How Fruit Flies Smell CO2
CO2 is an important source of information for insects. And the receptors that help them to detect it might also be useful for completely different applications. Mosquitoes in search of blood as well as fruit flies looking for a place to lay their eggs navigate using CO2, which is produced during respiration or in fermentation processes.

Life Sciences - Pharmacology - 12.01.2024
Cause of listlessness in depression discovered
Cause of listlessness in depression discovered
Lack of activation of the locus coeruleus in the brain inhibits the inner drive Researchers at the Max Planck Institute of Psychiatry in Munich, Germany,  have discovered that the dilation of the pupil in response to an expected reward depends on whether a person can feel pleasure. This indicates that insufficient activity of the locus coeruleus in the brain is largely responsible for the lack of drive in people with depression.

Life Sciences - Chemistry - 10.01.2024
Metabolic alteration to increase the stress tolerance of tobacco plants
Metabolic alteration to increase the stress tolerance of tobacco plants
Plant biotechnologists elucidate the mechanism that leads to higher seed yields in tobacco plants by transporting fatty acids - in addition to sugar - via the nutrient-carrying transport vessels When there is drought, a pathogen attack, or too much salt in the soil, plants are faced with a constant series of stress factors.

Health - Life Sciences - 09.01.2024
Main regulator for the body's oven discovered
Main regulator for the body’s oven discovered
Brown fat cells convert energy into heat - a key to eliminating unwanted fat deposits. In addition, they also protect against cardiovascular diseases. Researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Area "Life & Health" at the University of Bonn have now identified the protein EPAC1 as a new pharmacological target to increase brown fat mass and activity.

Life Sciences - 08.01.2024
A foreign language is transforming the brain
A foreign language is transforming the brain
Learning a second language strengthens neural connections in the language network in the left hemisphere of the brain Scientists at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig have unearthed fascinating evidence that the brain undergoes important changes in wiring when we embark on the journey of learning a new language in adulthood.

Health - Life Sciences - 08.01.2024
The gut microbiome prevents dangerous immune reactions
The gut microbiome prevents dangerous immune reactions
Certain combinations of gut bacteria protect stem cell transplantation patients After stem cell transplantation, the donated immune cells sometimes attack the patients' bodies. This is known as graft versus host disease or GvHD. Researchers at the Technical University of Munich (TUM) and the Universitätsklinikum Regensburg (UKR) have shown that GvHD is much less common when certain microbes are present in the gut.

Life Sciences - Psychology - 05.01.2024
How memories are formed in the brain - a new role for the internal compass
How memories are formed in the brain - a new role for the internal compass
Since their discovery in the 1990s, the head-direction cells in the brain have been referred to as its "internal compass." These cells are activated when the head of an animal or human points in a certain direction, and are thought to be important for spatial orientation and navigation. Now a team of neuroscientists at the University of Tübingen has discovered that head-direction cells in mice do more than this.

Health - Life Sciences - 05.01.2024
Prostate cancer: Newly-developed inhibitor shows massive potential
Prostate cancer: Newly-developed inhibitor shows massive potential
New epigenetic inhibitor is also effective in treatment-resistant prostate cancer cells More than 65,000 men fall ill with prostate cancer each year in Germany. Twelve thousand of them develop a treatment-resistant form which eventually ends in death. Now, a team of researchers from the Medical Faculty at the University of Freiburg has developed an active substance that might in future represent a new treatment option.

Life Sciences - Health - 03.01.2024
How Bacteria load their syringes
How Bacteria load their syringes
Pathogenic bacteria use molecular "shuttle services" to fill their injection apparatus with the right product Many bacterial pathogens use small injection apparatuses to manipulate the cells of their hosts, such as humans, so that they can spread throughout the body. To do this, they need to fill their syringes with the relevant injection agent.

Life Sciences - 21.12.2023
Big impacts from small changes in cell
Big impacts from small changes in cell
Research at Göttingen and Warwick Universities reveals how filament interactions affect cellular networks Tiny things matter - for instance, one amino acid can completely alter the architecture of the cell. Researchers at the Universities of Göttingen and Warwick investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin.

Environment - Life Sciences - 20.12.2023
Common insect species are suffering the biggest losses
Common insect species are suffering the biggest losses
Small Tortoiseshell butterflies (Aglais urticae) are an example of a species with formerly high local abundances that has declined in number. Insect decline is being driven by losses among the locally more common species, according to a new study published in "Nature".

Life Sciences - History / Archeology - 20.12.2023
Revealing close and distant relatives in ancient DNA with unprecedented precision
Revealing close and distant relatives in ancient DNA with unprecedented precision
Scientists have developed a new computational tool to detect up to second to third degree cousins using ancient genomes If two persons are biologically related, they share long stretches of DNA that they co-inherited from their recent common ancestor. These almost identically shared stretches of genomes are called IBD ("Identity by Descent") segments.

Life Sciences - 20.12.2023
First step towards synthetic CO2 fixation in living cells
First step towards synthetic CO2 fixation in living cells
Three modules forming a new-to-nature CO2 fixation cycle successfully implemented in E.coli Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2). Researchers at the Max-Planck-Institute for Terrestrial Microbiology have developed a synthetic biochemical cycle that directly converts CO2 into the central building block Acetyl-CoA.

Life Sciences - Health - 19.12.2023
When the Cellular Waste Collector Doesn't Show Up
When the Cellular Waste Collector Doesn’t Show Up
Researchers have identified a mechanism that promotes the breakdown of harmful protein deposits. If it malfunctions, it can lead to Parkinson's disease. NEMO, a protein that is primarily associated with signaling processes in the immune system, prevents the deposition of protein aggregates that occur in Parkinson's disease.