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News from the Lab (news.myScience.ch)

  • News from the Lab’ is a selection of scientific works that are significant or interesting for a broad readership. 
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Health - Life Sciences - 01.07.2022
Lung cancer: When radiation does not work
Lung cancer: When radiation does not work
Some lung tumors do not respond to radiation therapy. This effect can be reversed by blocking an enzyme in the tumor cells, as a Würzburg research team reports. Lung cancer is the most common cancer in the world, with 2.2 million new cases and around 1.8 million deaths in 2020 alone. While knowledge about the disease has improved considerably and new therapeutic strategies can prolong the lives of previously incurable patients, the figures clearly show that the mortality rate is still far too high.

Health - Life Sciences - 01.07.2022
A step on the way to better therapies against viruses
A step on the way to better therapies against viruses
Researchers from the MHH and RESIST show how a cell protein of the innate immune response prevents the multiplication of herpes viruses Most body cells can defend themselves against viruses after they have been activated by the body's own messenger substances (interferons). This happens with the help of proteins that recognise invading virus components and interfere with virus replication.

Health - 29.06.2022
Smoking promotes development of severe pulmonary hypertension
Smoking promotes development of severe pulmonary hypertension
Analysis of registry data leads MHH researchers to new insights into certain forms of the disease About one percent of the world's adult population suffers from pulmonary hypertension (PH). There are many forms of this disease. One of them is idiopathic pulmonary arterial hypertension (IPAH). This is a rare but very severe form of pulmonary hypertension.

Health - Psychology - 29.06.2022
New app helps Syrian refugees deal with post-traumatic stress
New app helps Syrian refugees deal with post-traumatic stress
Researchers at Leipzig University have partnered with Syrian refugees and an agency for e-mental health services to develop and scientifically test an app to help users deal with post-traumatic stress and related mental strain. The app - Sanadak - has now been published in Arabic and German and can be downloaded free of charge.

Health - Life Sciences - 28.06.2022
Signaling pathway in the brain to control food intake decoded
Signaling pathway in the brain to control food intake decoded
Binge eating bye bye: Signaling pathway in the brain to control food intake decoded A group of researchers has found a completely new approach to treating eating disorders. The scientists have demonstrated that a group of nerve cells in the hypothalamus (known as AgRP, agouti-related peptide neurons) control the release of endogenous lysophospholipids, which in turn control the excitability of nerve cells in the cerebral cortex, stimulating food intake.

Life Sciences - Health - 27.06.2022
Tracking down the causes of rare diseases in children
Tracking down the causes of rare diseases in children
The causes of intelligence impairment or epilepsy remain unexplained in more than 50 per cent of cases. Together with international colleagues, researchers at Leipzig University Hospital have discovered two genes with mutations that cause neurodevelopmental disorders in children. Their findings have now been published in scientific journals.

Life Sciences - Health - 24.06.2022
Importance of Selenium in the Opening Stages of Protein Synthesis
An international team of researchers with members from Freie Universität Berlin has made an important contribution to our understanding of the essential trace element selenium. The team was able to demonstrate how selenocysteine is incorporated into the proteins of eukaryotes. Using a specialized cryo-electron microscope, the researchers from Charité - Universitätsmedizin Berlin, the Max Planck Institute for Molecular Genetics, Rutgers University, New Jersey, USA, and the University of Illinois, Chicago, USA, succeeded in visualizing the first steps in selenoprotein synthesis.

Life Sciences - Health - 20.06.2022
Protein changes in the liquor indicate inflammatory processes in the brain
Alzheimer's, Parkinson's and other neurodegenerative diseases are associated with inflammatory processes in the brain. German researchers have succeeded in identifying a group of proteins in the liquor that could provide information about such inflammatory processes. As so-called biomarkers, the proteins could help to better understand disease processes in the future and to test the effect of potential drugs against brain inflammation.

Life Sciences - Health - 17.06.2022
Cell Biology: Diversity of centrosomes
Cell Biology: Diversity of centrosomes
Scientists from LMU and Helmholtz Munich have gained new insights into the human centrosome, whose malfunction is linked to many neurodevelopmental disorders. The centrosome is the organelle responsible for the organization of the cytoskeleton during cell division, an essential function in organisms from yeast to humans.

Health - Life Sciences - 15.06.2022
Custom-fit bacterial blockers
Custom-fit bacterial blockers
Similar to vaccines against the coronavirus, RNA-based antibiotics could decisively advance medicine. Research teams from Würzburg have investigated the requirements they must fulfill to achieve this. In the fight against the corona pandemic, mRNA-based drugs have impressively demonstrated their capabilities.

Health - Life Sciences - 15.06.2022
Precision antibacterials
Precision antibacterials
06/15/2022 Similar to the vaccines against the coronavirus, RNA-based antibiotics could significantly improve modern medicine. Research teams from Würzburg have investigated the prerequisites that such antibiotics must meet for this strategy to work. In the fight against the Covid-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential.

Health - Life Sciences - 10.06.2022
Thanks to umbilical cord stem cells: First successful treatment of severe pulmonary hypertension
Thanks to umbilical cord stem cells: First successful treatment of severe pulmonary hypertension
Hannover Medical School doctors successfully treat three-year-old girl. Clinical researchers at Hannover Medical School (MHH) have succeeded for the first time worldwide in stopping the usually fatal course of the disease in severe pulmonary hypertension thanks to a novel therapeutic approach. A three-year-old girl suffering from so-called pulmonary arterial hypertension (PAH) was treated for six months a total of five times with mesenchymal stem cell products obtained from a human umbilical cord.

Health - Innovation - 02.06.2022
3D printed, bioinspired heart valves
3D printed, bioinspired heart valves
Researchers have developed 3D printed artificial heart valves designed to allow a patient's own cells to form new tissue. To form these scaffolds using melt electrowriting - an advanced additive manufacturing technique - the team has created a new fabrication platform that enables them to combine different precise, customized patterns and hence to fine-tune the scaffold's mechanical properties.

Health - Pharmacology - 01.06.2022
Misperceptions about doctor's trust in Covid-19 vaccines influence vaccination rate
Misperceptions about doctor’s trust in Covid-19 vaccines influence vaccination rate
Informing people about the strong positive consensus among doctors persistently leads to increases in Covid-19 vaccinations How to increase vaccination rates by autumn, without any compulsion is shown by an international research team including the Max Planck Institute for Tax Law and Public Finance.

Social Sciences - Health - 31.05.2022
Healthy development thanks to older siblings
Healthy development thanks to older siblings
If expectant mothers are exposed to stress their child can develop behavioural problems - but this is less often the case for children with siblings During the first years of their lives, children develop the cognitive, social and emotional skills that will provide the foundations for their lifelong health and achievements.

Health - Pharmacology - 31.05.2022
Drug combination triples survival time with blood cancer
Drug combination triples survival time with blood cancer
MHH involved in international study on acute myeloid leukaemia (AML) Acute myeloid leukaemia (AML) is a malignant disease in which the precursor cells of the haematopoietic system multiply uncontrollably. This form of blood cancer is caused by genetic changes in the bone marrow that occur in the course of life.

Health - Pharmacology - 31.05.2022
Vaccination strategy can be optimised with computer model
HU research team simulates COVID-19 outbreaks with virtual agents A new model for simulating COVID-19 outbreaks helps to develop the right strategy for herd immunity for every municipality and city - even in the event of vaccine shortages. For, even after two years of the pandemic, countries, municipalities and cities are still experiencing severe COVID-19 outbreaks.

Life Sciences - Health - 31.05.2022
How invading pathogens switch off plant cells' defenses
How invading pathogens switch off plant cells’ defenses
Many disease-causing bacteria are able to inhibit the defense mechanisms in plants and thus escape dissolution by the plant cell, a process known as xenophagy. Animal and human cells have a similar mechanism whereby the cell's defenses -eat- invading bacteria - yet some bacteria can inhibit the process.

Health - Chemistry - 30.05.2022
Multi-functional bandage helps wounds to heal
Multi-functional bandage helps wounds to heal
Researchers at the Technical University of Munich (TUM) have developed a film that not only protects wounds similar to the way a bandage does, but also helps wounds to heal faster, repels bacteria, dampens inflammation, releases active pharmaceutical ingredients in a targeted manner and ultimately dissolves by itself.

Health - Computer Science - 27.05.2022
Same symptom - different cause?
Same symptom - different cause?
Machine learning is playing an ever-increasing role in biomedical research. Scientists at the Technical University of Munich (TUM) have now developed a new method of using molecular data to extract subtypes of illnesses. In the future, this method can help to support the study of larger patient groups.
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