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Health - Microtechnics - 19.09.2023
Cancer therapy: Microrobots explore cells - TUM
Cancer therapy: Microrobots explore cells - TUM
Opportunities for cancer treatment and wound healing Microrobots for the study of cells A group of researchers at the Technical University of Munich (TUM) has developed the world's first microrobot ("microbot") capable of navigating within groups of cells and stimulating individual cells. Berna Özkale Edelmann, a professor of Nanoand Microrobotics, sees potential for new treatments of human diseases.

Health - Pharmacology - 19.09.2023
Testing for long Covid: Eye exam as a new approach - TUM
Testing for long Covid: Eye exam as a new approach - TUM
Blood vessels in the eye altered with persistent coronavirus symptoms New approach to testing for long Covid A standardized eye examination might reveal in future whether people are suffering from long Covid syndrome or post-Covid. A team at the Technical University of Munich (TUM) was able to demonstrate a clear connection between the disease and certain changes to the blood vessels in the eye.

Life Sciences - Health - 18.09.2023
Larger brain area for language
Larger brain area for language
Language is one aspect that makes us human. The ability to produce an infinite number of utterances based on the words in the mental lexicon and a small number of syntactic rules is unique to humans. Other animals can learn words or calls and communicate, but the language ability of humans is unique.

Life Sciences - Health - 11.09.2023
How Internal Clocks Control Fat Metabolism
How Internal Clocks Control Fat Metabolism
In the fruit fly Drosophila, circadian clocks also control fat metabolism. This is shown in a new study by a research team at the University of Würzburg. The findings could also be relevant for humans. Much is known about how modern human lifestyles contribute to triggering metabolic disorders and diseases.

Health - Life Sciences - 11.09.2023
Consortium Discovers 28 New Risk Genes for COVID-19
Consortium Discovers 28 New Risk Genes for COVID-19
Researchers from the Institute of Human Genetics are involved in the work with their own study A great many criteria determine whether or not we get seriously ill from COVID-19. Besides our age and any previous or existing conditions, they also include genetic factors. Right from the start of the pandemic, the "COVID-19 Host Genetics Initiative" has been investigating the links between genetic factors and severe COVID-19.

Life Sciences - Health - 07.09.2023
How ribosome production and cell division rate are coupled
Scientists at Heidelberg University investigate functional details of a ribonucleoprotein complex for this circuitry. In order for cancer cells to divide continuously and unchecked, they have to outsmart the cellular mechanisms that normally ensure tight control of cell division. One of the elementary cellular processes is the production of ribosomes, which is manipulated by cancer cells in such a way that the ribosome production rate is ramped up, thus enabling the necessary high cell division rate.

Health - 07.09.2023
New compound unleashes the immune system on metastases
New compound unleashes the immune system on metastases
A new nanocomplex renders a tumor harmless - and, on top of that, it trains the immune system to detect and eliminate metastases. An international research team headed by Dr. Johannes Karges of the Faculty of Chemistry and Biochemistry at Ruhr University Bochum, Germany, has developed nanoparticles that accumulate in cancer cells and eliminate them after being photoactivated.

Health - Pharmacology - 06.09.2023
Ablation ensures survival benefits in terminal heart failure
In contrast to treatment with medication alone, patients benefit from additional catheter ablation, a new study shows. Heart specialists from the Heart and Diabetes Center NRW (HDZ NRW), Bad Oeynhausen, have demonstrated for the first time worldwide in a monocentric, open study that patients suffering from severe heart failure (cardiac insufficiency) in combination with symptomatic atrial fibrillation benefit more from catheter ablation in combination with guideline-compliant drug therapy than from drug therapy alone.

Health - Life Sciences - 06.09.2023
Potatos with the right antennae
Potatos with the right antennae
All over the world, huge quantities of crop protection agents are sprayed to control potato blight ( Phytophthora infestans ). The mechanisms of resistance of potatoes need to be better understood to make growing this crop more sustainable. Researchers of Wageningen University & Research together with their colleagues in Tübingen and Norwich have now taken an important step.

Health - Pharmacology - 05.09.2023
New approach in the treatment of non-alcoholic fatty liver disease (NAFLD)
The prebiotic resistant starch could play an important role in the treatment of non-alcoholic fatty liver disease (NAFLD) in the future. Initial indications suggest that a specially adapted diet with resistant starch not only positively influences the intestinal microbiome but also leads to an alleviation of the disease.

Health - 04.09.2023
How to inactivate common cold viruses
How to inactivate common cold viruses
There is something we can all do to prevent the common cold virus RSV from spreading: disinfecting hands and surfaces as well as gargling with mouthwash when symptoms occur. Every year, respiratory syncytial viruses (RSV) cause countless respiratory infections worldwide. For infants, young children and people with preexisting conditions, the virus can be life-threatening.

Health - Environment - 01.09.2023
How dangerous ticks really are in Germany
How dangerous ticks really are in Germany
Due to global warming and globalization, both ticks and tick-borne pathogens are spreading in Germany. The cross-institutional research project ,,E.ZE.SA: Pathogen spectrum of ticks in Saxony-Anhalt" has been collecting and analyzing data from tick findings by employees of the state's own forestry operations since 2019.

Health - Life Sciences - 29.08.2023
Hemp helps to heal
Hemp helps to heal
While the German government is planning to relax legislation on the use of cannabis, researchers from the Friedrich Schiller University Jena, together with colleagues from Italy, Austria and the USA, have identified the mode of action underlying anti-inflammatory effects demonstrated by cannabinoids.

Health - Pharmacology - 28.08.2023
High mortality from heart failure despite mechanical cardiovascular support
High mortality from heart failure despite mechanical cardiovascular support
Worldwide, there is a proliferation in the use of mechanical active cardiovascular support. The hope is to use these assist devices to improve survival after the most severe form of acute heart failure, cardiogenic shock. A recent clinical study, led by heart specialist Prof. Holger Thiele, has shown that these devices do not reduce mortality after cardiogenic shock within 30 days.

Health - Sport - 25.08.2023
Online training shows positive effect after surgery for cancer patients
Positive effects of physical activity are fundamentally known for cardiovascular, metabolic and cancer diseases. However, the physical distance to physical activity centers is often a barrier. That's why researchers at the University of Leipzig have now tested whether app-based home exercise, including digital activity feedback via a smartwatch, works well for cancer patients after surgery.

Health - Pharmacology - 25.08.2023
Adrenocortical carcinoma: No mitotane for low risk of recurrence
Adrenocortical carcinoma: No mitotane for low risk of recurrence
After the complete tumour resection, not all patients with an adrenocortical carcinoma require the previous standard therapy Mitotane. Professors Martin Fassnacht and Massimo Terzolo show this in a clinical trial. In 2017, the teams of Massimo Terzolo and Martin Fassnacht published a study in the New England Journal of Medicine that provided evidence for the efficacy of Mitotane in the prevention of recurrence in adrenocortical carcinoma.

Health - Pharmacology - 21.08.2023
Timing is key
Whether you have a sports injury, repetitive strain injury or pain in the knee, cortisone preparations are often used to treat acute inflammations. Chronic inflammatory diseases such as asthma, diabetes and chronic inflammatory bowel diseases are also treated with drugs containing cortisone or derived drugs.

Life Sciences - Health - 17.08.2023
Previously unknown function: Noelin proteins central for learning ability in mammalian brains
Previously unknown function: Noelin proteins central for learning ability in mammalian brains
German-American research team reveals the fundamental importance of Noelin proteins for the activity-dependent plasticity of nerve cells A German-American research team headed by Bernd Fakler from the Faculty of Medicine at the University of Freiburg demonstrated the major influence of Noelin1-3 proteins on learning and memory formation in the mammalian brain.

Health - Pharmacology - 17.08.2023
Anti-obesity drug improves associative learning in people with obesity
Obesity leads to altered energy metabolism and reduced insulin sensitivity of cells. The so-called "anti-obesity drugs" are increasingly used to treat obesity and have caused tremendous interest, especially in the USA. Researchers at the Max Planck Institute for Metabolism Research in Cologne, Germany, have now shown in people with obesity that reduced insulin sensitivity affects learning of sensory associations.

Life Sciences - Health - 10.08.2023
Tricking Harmful Mutations
Tricking Harmful Mutations
An international research team headed by Zoya Ignatova from Universität Hamburg has developed an innovative strategy for using artificially construed transfer RNA (tRNA) to suppress genetic mutations. These mutations can lead to serious diseases. The tests, which have been successfully conducted using patients- cells and mice, could yield new approaches to fighting different, currently incurable diseases.
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