The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, the composition of which has so far been a mystery to scientists. Researchers at the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) have now succeeded in deciphering the function of this unusual arrangement. By modifying the protein structure, the pathogenicity of the fungus could also be reduced. The new findings were used to render the fungal toxin harmless with the help of artificial antibodies. ...
