New pathway in immune defense discovered

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Bonn researchers decode the interaction of monocytes and platelets in human blood

From left: -   Ibrahim Hawwari,   Bernardo Franklin and Lukas Roßnagel discover
From left: - Ibrahim Hawwari, Bernardo Franklin and Lukas Roßnagel discover a new intercellular communication mechanism in which blood platelets, so-called thrombocytes, regulate the function of monocytes. © Photo: UKB/Alessandro Winkler all’images in original size .
Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have now discovered that platelets, also known as thrombocytes, communicate with monocytes and increase their inflammatory capacity. By understanding the platelet-monocyte interaction, they hope to improve the treatment of immune disorders and associated diseases. ...
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