A team at the Helmholtz Centre for Infection Research in Würzburg, Germany, led by RNA expert Chase Beisel, has developed a new technology for the precise detection of RNA using DNA-cutting Cas12 nucleases.
CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg have expanded this extensive toolbox. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy. ...
