Active Plant Substance Reduces Pulmonary Hypertension

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Daniela Wenzel, Michaela Matthey and Alexander Seidinger (from left) tested the
Daniela Wenzel, Michaela Matthey and Alexander Seidinger (from left) tested the effect of the substance FR on pulmonary hypertension. RUB, Marquard
A substance derived from the plant Ardisia crenata works in a different way than existing drugs. And in doing so, it is highly effective.

Pulmonary hypertension is a very serious disease that leads to heart failure and death in many patients. Searching for new treatment options, a team headed by Professor Daniela Wenzel and Alexander Seidinger from the Department of Systems Physiology at Ruhr University Bochum, Germany, tested the plant substance FR900359 - referred to as FR by the researchers. It differs from previously used active substances in that it targets a different point in the signaling pathway that leads to pulmonary hypertension. As a result, it simultaneously inhibits numerous factors that lead to vasoconstriction in the lungs. ...
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