Vitamin B2 Derivatives Can Alleviate Chronic Kidney Inflammation

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Immunofluorescence - staining of MAIT cells (green) next to mononuclear phagocyt
Immunofluorescence - staining of MAIT cells (green) next to mononuclear phagocytes (red) in kidney sections of mice with experimental glomerulonephritis. Cell nuclei in blue. © Image: Nature Communications, DOI: 10.1038/s41467’023 -43269-0 all images in original size All rights reserved!
Researchers from the University Medical Center Hamburg-Eppendorf and the University Hospital Bonn have demonstrated that certain derivatives of vitamin B2 can alleviate chronic kidney inflammation in mice. Their findings have been published in the journal "Nature Communications." 

The term glomerulonephritis denotes several types of chronic kidneys inflammation that can lead to the loss of renal function. Most of these conditions are due to autoaggressive immune responses that damage the kidney tissue. Although glomerulonephritis can be treated with immunosuppressive drugs such as corticosteroids, sometimes there is no way of stopping the self-destructive immune response. ...
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