Repelling disorder: What makes cholesterol-containing surfaces so repulsive?

Die Collembole Tetrodontophora bielanensis in ihrem natürlichen Lebensraum. Foto
Die Collembole Tetrodontophora bielanensis in ihrem natürlichen Lebensraum. Foto: Stephan Floss/Leibniz Institut für Polymerforschung Dresden
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Living organisms use powerful physical principles to control interactions at their surfaces. Researchers at the Leibniz Institute of Polymer Research Dresden, Leipzig University and TU Dresden have now discovered why cholesterol-containing surfaces can exhibit greatly reduced attachment of proteins and bacteria.

The interdisciplinary team led by Carsten Werner had previously identified cholesterol as a component of the skin of widespread invertebrates (collembolae), which breathe through their skin and therefore need to protect it from contamination. In their paper published in Nature on 22 June 2023, the scientists have now elucidated a repulsive mechanism of cholesterol-containing surfaces. ...
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