Protein stock for the beginning of a new life
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Cytoplasmic lattices in the egg cell supply the early embryo as protein storage sites
A mouse egg cell, naturally filled with the protein PADI6 (blue) - a marker and main component of the cytoplasmic lattice. The DNA in the cell nucleus is shown in magenta. When mammals have offspring, they invest a lot. Unlike fish or frogs, the embryo cannot develop on its own. It has to implant in the uterus, where it is supplied with everything it needs to survive. Until this happens, the egg cell nourishes the early embryo. Among other things, it provides essential proteins. Researchers led by Melina Schuh at the Max Planck Institute for Multidisciplinary Sciences, together with colleagues in Göttingen, have now elucidated how egg cells store proteins. Their experiments also provide important insights into how errors in protein storage can lead to infertility. ...TO READ THIS ARTICLE, CREATE YOUR ACCOUNT
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