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Results 41 - 49 of 49.


Health - Pharmacology - 24.03.2023
Novel Regulatory Mechanism of Blood Clotting Discovered
The glycoprotein V of the blood platelets is an important switch point for haemostasis and thrombus formation. This new finding could have great clinical potential. When our blood vessels are injured by cuts, abrasions, or bruises, it is vital that the bleeding is stopped, and the wound is sealed. This process is called hemostasis and involves two main components: First, blood platelets attach to the wound edges, form a plug and provisionally seal the injury.

Health - Pharmacology - 21.03.2023
Targeted computer modelling to accelerate antiviral drug development
Targeted computer modelling to accelerate antiviral drug development
Effective drugs against viral diseases like COVID-19 are urgently needed now and in the future. The emergence of viral mutants and yet unknown viruses could push vaccines to their limits. The DZIF scientist and bioinformatician Andreas Dräger from the University of Tübingen is working on a computer-based method that can help to accelerate the time-consuming identification and development of antiviral agents.

Health - Pharmacology - 20.03.2023
Milestone in pulmonary hypertension therapy
Milestone in pulmonary hypertension therapy
In pulmonary arterial hypertension (PAH), the small vessels in the lungs become increasingly narrow and obstruct the transport of blood to the lungs. A new drug can stop this change and possibly even reverse it. Pulmonary arterial hypertension (PAH) is a special form of pulmonary hypertension. It occurs because the small arteries in the lungs narrow as a result of progressive changes in the blood vessels.

Pharmacology - Health - 14.03.2023
Receptor 'blasting' visualised
Receptor ’blasting’ visualised
Adhesion GPCRs are a group of G protein-coupled receptors associated with many body functions and diseases. However, they have not yet been sufficiently studied to be used for therapies. Two research groups at the Rudolf Schönheimer Institute at the Faculty of Medicine at Leipzig University have now jointly developed a technology to change this.

Health - Pharmacology - 01.03.2023
Artificial intelligence to help tumor immunology
Artificial intelligence to help tumor immunology
Researchers want to study the environment of cancer cells in more detail. Federal Ministry of Education and Research funds project with 800,000 euros The success of cancer treatment depends not only on the type of tumor, but also on the surrounding tissue. Tumors influence it to their advantage, promoting the growth of blood vessels or fooling incoming immune cells.

Pharmacology - Health - 19.01.2023
New hope for treatment of rare metabolic disease
Results of a controlled clinical trial with a new drug for the treatment of X-linked adrenoleukodystrophy To date, no pharmacological treatment exists for X-linked adrenoleukodystrophy, a progressive genetic metabolic disease that damages the adrenal glands, the spinal cord and the white matter of the nervous system.

Health - Pharmacology - 17.01.2023
Endogenous molecule protects from life-threatening complications after stem-cell transplantation
Endogenous molecule protects from life-threatening complications after stem-cell transplantation
Freiburg researchers find that an antimicrobial molecule modifies T-cell-signalling and thus attenuates overshooting immune reactions Acute Graft-versus-host disease (GvHD) is a life-threatening complication after leukemia treatment with allogeneic stem cell transplantation, i.e. the transplantation of cells from another person.

Pharmacology - Life Sciences - 17.01.2023
Paderborn scientist is researching new approaches to combat antibiotic-resistant germs
Paderborn scientist is researching new approaches to combat antibiotic-resistant germs
Dr. Adrian Keller receives Paderborn University Research Award Antibiotics are regularly used in medicine to fight bacterial infections. However, resistant germs to which drugs are unable to respond are now increasingly emerging, especially in hospitals. This is because as bacteria reproduce and further develop, their genetic material - i.e. their DNA - can change to make them resistant to antibiotics.

Health - Pharmacology - 06.01.2023
Simply resolving inflammation through the flick of a switch
Simply resolving inflammation through the flick of a switch
Chronic inflammatory processes are the most common causes of a variety of widespread diseases. They play a role in arthritis, asthma, Parkinson's disease and Alzheimer's disease, but also in arteriosclerosis, diabetes and cancer. Drugs that inhibit inflammation are, therefore, among the medicines that are taken most frequently worldwide.