news 2023

« BACK

Pharmacology



Results 21 - 40 of 49.


Health - Pharmacology - 04.07.2023
Does blood purification help against severe fatigue in post-COVID?
Does blood purification help against severe fatigue in post-COVID?
Chronic fatigue syndrome (CFS) is a heavy burden. The "EXTINCT post COVID" project is investigating the effectiveness of apheresis therapy and is seeking participants for a study. The Corona pandemic seems to have been overcome; mandatory masks and other restrictions have largely been abolished. However, about one in ten people continue to suffer the consequences of a Corona infection for longer: persistent fatigue, exhaustion, heart problems, poor concentration and shortness of breath.

Health - Pharmacology - 22.06.2023
New weapon against hepatitis D
New weapon against hepatitis D
In a multicentre phase 3 trial, researchers at the MHH have demonstrated the efficacy and safety of the drug Bulevirtide, which prevents HD viruses from entering the liver. Infection with hepatitis D virus (HDV) causes the most severe form of chronic, viral hepatitis disease. About ten to 20 million people worldwide are affected.

Health - Pharmacology - 21.06.2023
Single hepatitis E mutation renders sofosbuvir therapy ineffective
Single hepatitis E mutation renders sofosbuvir therapy ineffective
A single mutation stands in the way of a drug's effectiveness. Understanding it helps find new therapeutic approaches. So far, there are no specific drugs to treat the hepatitis E virus. Doctors only have the broad-spectrum antiviral drug ribavirin at their disposal, which is often associated with severe side effects.

Health - Pharmacology - 13.06.2023
Nasal Vaccine against Coronavirus Further Improved
Research team at Freie Universität Berlin increases safety of attenuated live SARS-CoV-2 vaccine After having successfully tested a mucosal vaccine against coronavirus in animals just months ago, Berlin scientists have now further developed their live SARS-CoV-2 vaccine. Researchers at Freie Universität Berlin have increased the safety of the vaccine, which is administered via the nose.

Pharmacology - 02.06.2023
Neutrons show how pre-filled syringes clog
Neutrons show how pre-filled syringes clog
The hypodermic needles on pre-filled syringes can clog when stored incorrectly. A research team subjected the process to a detailed and systematic investigation, including activities at the Research Neutron Source Heinz Maier-Leibnitz (FRM II) of the Technical University of Munich (TUM). The results will help improve manufacturing and storage conditions accordingly.

Pharmacology - Health - 25.05.2023
Schizophrenia drug as new therapy against dementia
Schizophrenia drug as new therapy against dementia
A clinical trial will investigate the drug's efficacy in dementia patients. A common feature of many neurodegenerative diseases are pathological protein deposits in the brain. These protein aggregates cause nerve cells to die and, as a result, entire brain areas to shrink, which manifests itself in affected individuals as progressive dementia.

Pharmacology - 22.05.2023
New measurement equipment at the University: Studying receptor proteins using EPR spectroscopy
New measurement equipment at the University: Studying receptor proteins using EPR spectroscopy
News from Studying proteins with novel methods is Dr Matthias Elgeti's speciality. An EPR spectrometer is helping him to study the structure and dynamics of G protein-coupled receptors (GPCRs). His work is concerned with the side effects of drugs and the regulation of bodily functions such as hunger.

Chemistry - Pharmacology - 17.05.2023
New method to synthesise cannabis plant compound
New method to synthesise cannabis plant compound
Cis-tetrahydrocannabinoids can now be produced synthetically, enabling pharmaceutical applications A group of researchers at Leipzig University has developed a new method for synthesising cis-tetrahydrocannabinol (THC) - a natural substance found in the cannabis plant that produces the characteristic psychoactive effect and has many potential applications, including in the pharmaceutical industry.

Health - Pharmacology - 15.05.2023
Dementia: Advocacy for early diagnosis declining, knowledge of risk factors expandable
The number of people with dementia is increasing. Therefore, early detection and diagnosis of the age-related disease are becoming increasingly important. Researchers at the Institute of Social Medicine, Occupational Medicine and Public Health (ISAP) at the University of Leipzig have conducted a representative survey to investigate the attitudes of people aged 60 and over toward early diagnosis of dementia: they analyzed data from two telephone surveys and compared the results.

Health - Pharmacology - 12.05.2023
Resistant fungal species spreads
Resistant fungal species spreads
The number of infections with the fungus Candida auris is also increasing in Germany. This is shown in a new study by research teams from Würzburg, Jena and Berlin. Despite low numbers, scientists advise precautionary measures. Among the yeasts from the Candida genus that cause infections in humans, the species Candida auris is still relatively new: this species was only described in 2009, and to date no evidence has been found before the 1990s.

Health - Pharmacology - 12.05.2023
Resistant fungal species spreads
Resistant fungal species spreads
The number of infections with the fungus Candida auris is also increasing in Germany. This is shown in a new study by research teams from Würzburg, Jena and Berlin. Despite low numbers, those involved advise precautionary measures . Among the yeasts of the genus Candida that cause infections in humans, the species Candida auris is still relatively new: this species was only described in 2009, and to date no evidence has been found before the 1990s.

Pharmacology - Health - 08.05.2023
Prolonging the survival of patients with gastric cancer
Prolonging the survival of patients with gastric cancer
International study shows that treating gastric cancer with new antibody has positive effects Gastric cancer is the fifth most commonly diagnosed malignancy worldwide. It ranks a sad third in cancer-related causes of death. The reason for this is late diagnosis coupled with rapid spread of tumour cells in the body.

Health - Pharmacology - 05.05.2023
Innovative 3D drug screening system
Innovative 3D drug screening system
Biophysicist at Göttingen University receives ERC Proof of Concept Grant Professor Timo Betz, University of Göttingen, has been awarded a Proof of Concept (PoC) grant by the European Research Council (ERC) for his -TissMec- project to develop a 3D screening system to cultivate tissue and automatically stimulate and quantify its mechanical properties.

Health - Pharmacology - 04.05.2023
Gamma delta T cells can fight aggressive breast cancer
Gamma delta T cells can fight aggressive breast cancer
Freiburg researchers discover a mechanism by which cancer cells escape the immune system. Triple-negative breast cancer (TNBC) is the most aggressive and deadly form of breast cancer with limited treatment options and a high probability of recurrence. Tumor growth and relapse of TNBC are driven by breast cancer stem cells, and improved therapies that can eliminate those hardy cells are urgently needed.

Pharmacology - Health - 26.04.2023
How to increase the chance of survival in older patients with head and neck cancer
How to increase the chance of survival in older patients with head and neck cancer
Should patients over the age of 70 with head and neck cancer receive aggressive combined radiotherapy and chemotherapy? This is a controversial issue among patients, their families and health professionals. A large-scale international study involving Leipzig University Hospital proves the effectiveness of this combined treatment in older patients.

Pharmacology - Environment - 21.04.2023
Toxicity of drugs released into waterways partly depends on acidity
A study by researchers from the Universities of Tübingen and Athens has found that the toxicity of chemicals in lakes and rivers may vary by several orders of magnitude depending on the water's acidity. Professor Heinz Köhler from the University of Tübingen's Institute of Evolution and Ecology, working with colleagues from Athens and the German Environment Agency, tested the effect of 24 substances, most of which are used as drugs, on the development of fish embryos in realistic scenarios.

Health - Pharmacology - 17.04.2023
New treatment option for bile duct cancer
New treatment option for bile duct cancer
International study with participation of MHH Professor Arndt Vogel shows improved overall survival with immunotherapy New cases of bile duct cancer, also known as biliary tumours, are increasing worldwide. The chances of cure are considered poor. The standard therapy for advanced bile duct cancer has so far been based on chemotherapy with the therapeutic agents gemcitabine and cisplatin; treatment with the body's own immune defence system has been researched for years for this type of cancer.

Physics - Pharmacology - 11.04.2023
Neutrons for better vaccines against multidrug resistant germs
Neutrons for better vaccines against multidrug resistant germs
Reading time 3 min. FRM II lets scientists look deep inside the structure of biomolecules Neutrons from the Research Neutron Source Heinz Maier-Leibnitz (FRM II) can be used to explore the structure of biomolecules. The most recent success: the precise analysis of a promising vaccine against multidrug resistant germs.

Pharmacology - Health - 30.03.2023
How to achieve a functional cure for chronic hepatitis B
More than half of people with chronic hepatitis B have a form of the disease in which the immune system almost never achieves sustained control, despite many years of treatment. According to current knowledge, those affected therefore require lifelong drug therapy. In the world's first study on the discontinuation of treatment with the common antiviral drug for the severe form called HBeAg-negative hepatitis B, scientists have shown that some patients can achieve sustained immune control if they discontinue the antiviral therapy after a certain period of time.

Health - Pharmacology - 27.03.2023
Components of Cytoskeleton Strengthen Effect of Sex Hormones
Components of Cytoskeleton Strengthen Effect of Sex Hormones
Researchers from Freiburg and Kiel discover that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics Steroid hormones, to which belong sex hormones like estrogen or testosterone, are important signaling molecules and are responsible among other things for controlling female and male phenotypic sex differentiation.