Inhibitory Signals in Visual Neurons Protect Against Overstimulation

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Zebrafish larvae with (left) and without (right) green fluorescing protein in th
Zebrafish larvae with (left) and without (right) green fluorescing protein in the areas of the brain (tectum) that process visual information. Photograph: Johann Bollmann.

Freiburg neuroscientists identify signals in the brain of zebrafish larvae that suppress the activity of nerve cells during locomotion

When the eye jumps from one point to another, the image of our surroundings rapidly passes across the retina and triggers a wave of neuronal activity. In order not to be overwhelmed by the sensory impressions produced by our own movements, the brain suppresses processing of the stimuli as this happens. Now, researchers headed by Freiburg neuroscientist Professor Johann Bollmann have for the first time measured the signals that do this at a cellular level in zebrafish larvae. Their results have been published in Nature Communications.

Rather than moving at a steady speed, zebrafish larvae swim in erratic bouts. ...

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