How Immune Cells Recognize their Enemies

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The figure shows how close BTN3 molecules come to each other in the cell by comp
The figure shows how close BTN3 molecules come to each other in the cell by comparing BTN3A1 molecules with modified BTN3A1 molecules. The color blue/turquoise stands for no or little interaction and thus a greater distance. Green and red show a stronger interaction, i.e. closer proximity. (Image: AG Thomas Herrmann)

In order for immune cells to do their job, they need to know against whom they should direct their attack. Research teams at the University of Würzburg have identified new details in this process.

As complicated as their name is, they are important for the human organism in the fight against pathogens and cancer: V’9V’2 T cells are part of the immune system and, as a subgroup of white blood cells, fight tumor cells and cells infected with pathogens. ...

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