Andrea Rentmeister's team detects methylated sites with click chemistry The genetic information of an organism is stored in the form of DNA (deoxyribonucleic acid) in every cell. In order to be able to produce proteins with this blueprint, the DNA is first transcribed into so-called mRNA (messenger ribonucleic acid).

It's quite obvious that they are involved. The latest findings show one possible way. Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death. Although the causal link between protein aggregates and neurodegeneration is clear, it is still unclear in what way misfolded proteins trigger cell death.

A study led by education professor Martin Neugebauer of Freie Universität Berlin and published in the European Sociological Review shows that young people's life satisfaction significantly declined during the pandemic Young people faced particularly difficult challenges during the Covid-19 pandemic.

Simple plastics made from polyolefins such as films or carrier bags have become an integral part of our everyday lives, but are rarely recycled. Junior Professor Robert Geitner wants to give these food packaging materials a new lease of life. At his Physical Chemistry/Catalysis Group, he is researching new potential applications for the materials.

Protein droplets reveal new ways to inhibit transcription factors in an aggressive form of prostate cancer Many of the most potent human oncoproteins belong to a class of proteins called transcription factors, but designing small molecule drugs that target transcription factors is a major challenge.

Planets like our Earth could form even in the harshest known star-forming environments, drenched by hard UV light from massive stars. That is a main result of analyses of new observations of such an environment with the James Webb Space Telescope. The observations are the first of their kind - before James Webb, this kind of detailed observation had not been possible.

Study by the Universities of Bonn and St. Andrews proposes a solution to one of the great mysteries of cosmology The universe is expanding. How fast it does so is described by the so-called Hubble-Lemaitre constant. But there is a dispute about how big this constant actually is: Different measurement methods provide contradictory values.

Good news for researchers working with high-resolution fluorescence microscopy: Biocompatible molecular rulers are available for the first time to calibrate the latest super-resolution microscopy methods. Latest super-resolution microscopy methods now achieve an optical resolution in the range of a few nanometres.

School students experience a wide range of achievement emotions during the years they spend attending school. Some of those emotions, such as joy and pride, are positive. Yet students also experience boredom and anger when they find achievement activities too difficult or too easy. These differing emotions are important for adolescents' development trajectories.

In today's medical landscape, antibiotics are pivotal in combatting bacterial infections. These potent compounds, produced by bacteria and fungi, act as natural defenses against microbial attacks. A team of researchers delved into the intricate world of glycopeptide antibiotics - a vital resource in countering drug-resistant pathogens - to uncover their evolutionary origins.

Freiburg neuroscientists identify signals in the brain of zebrafish larvae that suppress the activity of nerve cells during locomotion When the eye jumps from one point to another, the image of our surroundings rapidly passes across the retina and triggers a wave of neuronal activity. In order not to be overwhelmed by the sensory impressions produced by our own movements, the brain suppresses processing of the stimuli as this happens.

To ensure safe and efficient traffic, the various objects in road and air traffic must be able to quickly detect their spatial environment using radar and communicate with each other via radio networks. In order to investigate the radar reflection of a so-called VTOL drone (short for "Vertical Take-Off and Landing"), which can take off and land vertically without a runway, the Electronic Measurements and Signal Processing (EMS) Group at TU Ilmenau has set up a test facility at the BiRa test facility has just completed an extensive measurement campaign at the BiRa test facility.

When it comes to self-discipline, psychological research traditionally focuses on individual responsibility. Wilhelm Hofmann believes this is too short-sighted. Self-discipline doesn't work without effective regulation. While many people want to achieve major long-term goals - such as improving their diet, quitting smoking or adopting a more sustainable lifestyle - they often find it difficult to do so.

New study shows the most fragmented sleep ever recorded in an animal When breeding in a dangerous environment, chinstrap penguins usually do not nod off for more than four seconds at a time. However, they still get up to twelve hours of sleep in total thanks to over 600 such microsleep phases per hour - and over 10,000 per day.

University of Bonn study shows where diversified farming also makes economic sense Where and how can diversified farming practices be put to profitable use in order to boost both productivity and biodiversity? Researchers at the University of Bonn have tackled this question in a study that has now been published in "Communications Earth & Environment.

Formaldehyde can inhibit enzymes that produce hydrogen particularly efficiently. Researchers from Bochum have discovered how this can be prevented. Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. In order to make this hydrogen production efficient, researchers are trying to identify and eliminate possible limiting factors.

TUM researchers develop rapid test for severe infections Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe COVID-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a COVID-19 infection.

Heidelberg scientists unveil genetic programmes controlling the development of cellular diversity in the cerebellum of humans and other mammals The evolution of higher cognitive functions in human beings has so far mostly been linked to the expansion of the neocortex - a region of the brain that is responsible, inter alia, for conscious thought, movement and sensory perception.

Efficient removal of abnormal myelin allows survival of nerve fibers targeted by adaptive immune cells, according to a novel study by scientists of the University Hospital Würzburg. Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins.

Researchers led by Göttingen University determine factors for chemical development in crater lakes on Earth In southern Germany just north of the Danube, there lies a large circular depression between the hilly surroundings: the Nördlinger Ries. Almost 15 million years ago, an asteroid struck this spot.