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Health - Computer Science - 27.05.2022 
Same symptom - different cause?
Machine learning is playing an ever-increasing role in biomedical research. Scientists at the Technical University of Munich (TUM) have now developed a new method of using molecular data to extract subtypes of illnesses. In the future, this method can help to support the study of larger patient groups.
Health - Sport - 25.05.2022 
Link between exercise intensity and risk of infection
Until now there has been no clarity on how exercise intensity affects the emission and concentration of aerosol particles in exhaled air. With a new experimental setup, a Munich research team has shown that aerosol emissions increase exponentially with intense physical exertion - so that indoor sporting activities result in a higher risk of infectious diseases such as COVID.
Health - Life Sciences - 25.05.2022
Health - Life Sciences - 25.05.2022 
Secrets of thymus formation revealed
Max Planck researchers identify epithelial stem cells that control the growth of the thymus at different stages of life Many immune cells crucial for our immune system develop in a small organ next to our heart: the thymus. With age, however, the thymus shrinks, and the number of effective immune cells declines.
Chemistry - Health - 20.05.2022
Health - Life Sciences - 19.05.2022
Health - Life Sciences - 18.05.2022 
On the trail of urinary tract infections
05/18/2022 The German government is providing about 2.4 million Euros for a new research group in infectious diseases at JMU Würzburg. Dr. Carmen Aguilar will use this grant to search for new therapeutic approaches against one of the most common and recurrent bacterial infections. About every second woman gets a urinary tract infection once in her life, the cause for which is most often the uropathogenic bacterium Escherichia coli (UPEC).
Health - Life Sciences - 13.05.2022 
’Growing end’ of inflammation discovered
Researchers from the Universities of Bonn and Cologne observe how the danger sensor NLRP3 lengthens itself like a thread Redness, swelling, pain - these are signs of inflammation. It serves to protect the body from pathogens or foreign substances. Researchers from the Universities of Bonn and Cologne were able to show that inflammatory reactions of an important sensor protein proceed in a specific spatial direction.
Health - Life Sciences - 12.05.2022
Life Sciences - Health - 10.05.2022 
Rare discovery: How a gene mutation causes higher intelligence
When genes mutate, this can lead to severe diseases of the human nervous system. Researchers at Leipzig University and the University of Würzburg have now used fruit flies to demonstrate how, apart from the negative effect, the mutation of a neuronal gene can have a positive effect - namely higher IQ in humans.
Life Sciences - Health - 06.05.2022 
Animal research: influence of experimenters on results less strong than expected
For more than ten years now, scientists have been discussing the so-called reproducibility crisis: often, scientific findings cannot be reproduced at a later time and/or in other laboratories, although the studies are carried out under highly standardised conditions. Thereby, standardisation includes for example the use of genetically identical animals, keeping the animals in identically equipped cages, and carrying out the experiments in always the same way.
Pharmacology - Health - 05.05.2022 
Small changes - but essential! How peptides are recognised in receptors
Researchers discover molecular mechanisms of signal recognition of the neuropeptide system The human body consists of trillions of cells that constantly communicate with each other. A central role in this communication process is played by receptor proteins on the cell surface. Since they often serve as drug targets, they have been the subject of intensive research.
Politics - Health - 05.05.2022
Life Sciences - Health - 04.05.2022 
The fungal effector Rip 1 suppresses maize host defense responses
Coevolution between pathogens and host plant immune systems shapes a multifaceted network of interactions that remain phenotypically unrecognised and functionally elusive unless single players are depleted from the system. The maize-colonising fungus Ustilago maydis secretes a complex effector blend in order to suppress defence and redirect host metabolism in its favour.
Materials Science - Health - 28.04.2022 
Bones, constructed like prestressed concrete
Incorporating various minerals in collagen puts these composite materials under stress and makes them particularly hard and strong What engineers discovered only about 100 years ago has been used by nature for as long as vertebrates have existed. Just as steel wires under strain increase the fracture resistance of prestressed concrete, bones become particularly hard and strong because their collagen fibres are under stress due to embedded mineral nanoparticles.
Health - Pharmacology - 28.04.2022 
Vaccination campaign messages often prove ineffective
Conventional vaccination campaign messages often miss their targets. A study in eight European countries shows that information on the benefits of vaccines can even reduce the willingness to get immunized. The researchers also looked into the factors that influenced the impact of messages, including low health literacy.
Health - Pharmacology - 26.04.2022
Health - Life Sciences - 25.04.2022
Health - Life Sciences - 22.04.2022 
A Low-Calorie Diet Alters the Gut Microbiome and Delays Immune Aging
Around 2 billion people worldwide are overweight. Obesity increases the risk of developing high blood pressure, heart attack or type 2 diabetes mellitus and can cause inflammation in the body that weakens the immune system through an accumulation of specific memory T and B cells. This process is called immune senescence, an age-related change in the immune system.
Life Sciences - Health - 22.04.2022
Health
Results 1 - 20 of 68.
Machine learning is playing an ever-increasing role in biomedical research. Scientists at the Technical University of Munich (TUM) have now developed a new method of using molecular data to extract subtypes of illnesses. In the future, this method can help to support the study of larger patient groups.
Until now there has been no clarity on how exercise intensity affects the emission and concentration of aerosol particles in exhaled air. With a new experimental setup, a Munich research team has shown that aerosol emissions increase exponentially with intense physical exertion - so that indoor sporting activities result in a higher risk of infectious diseases such as COVID.
A potential fountain of youth for the immune system
05/25/2022 In old age, the performance of the immune system decreases, and older people are more susceptible to infections. Research teams from Würzburg and Freiburg have now discovered an approach that could be used to slow down this process. The corona pandemic has made it clear: Older people are more susceptible to infections, suffer from more severe infectious diseases than young people, and they take significantly longer to recover.
05/25/2022 In old age, the performance of the immune system decreases, and older people are more susceptible to infections. Research teams from Würzburg and Freiburg have now discovered an approach that could be used to slow down this process. The corona pandemic has made it clear: Older people are more susceptible to infections, suffer from more severe infectious diseases than young people, and they take significantly longer to recover.
Max Planck researchers identify epithelial stem cells that control the growth of the thymus at different stages of life Many immune cells crucial for our immune system develop in a small organ next to our heart: the thymus. With age, however, the thymus shrinks, and the number of effective immune cells declines.
Mini-fuel cell generates electricity using the body’s sugar
Glucose energy source for medicinal implants and sensors Mini-fuel cell generates electricity using the body's sugar Glucose is the most important energy source in the human body. Scientists at the Technical University of Munich (TUM) and the Massachusetts Institute of Technology (MIT) now want to use the body's sugar as an energy source for medicinal implants.
Glucose energy source for medicinal implants and sensors Mini-fuel cell generates electricity using the body's sugar Glucose is the most important energy source in the human body. Scientists at the Technical University of Munich (TUM) and the Massachusetts Institute of Technology (MIT) now want to use the body's sugar as an energy source for medicinal implants.
New method revolutionizes cancer diagnosis
"Deep Visual Proteomics" technology provides cell-specific, protein-based information and helps to analyze cancer diseases How does cancer arise? How does cellular composition influence tumor malignancy? These questions are profound and challenging to answer, but are crucial to understand the disease and find the right cure.
"Deep Visual Proteomics" technology provides cell-specific, protein-based information and helps to analyze cancer diseases How does cancer arise? How does cellular composition influence tumor malignancy? These questions are profound and challenging to answer, but are crucial to understand the disease and find the right cure.
05/18/2022 The German government is providing about 2.4 million Euros for a new research group in infectious diseases at JMU Würzburg. Dr. Carmen Aguilar will use this grant to search for new therapeutic approaches against one of the most common and recurrent bacterial infections. About every second woman gets a urinary tract infection once in her life, the cause for which is most often the uropathogenic bacterium Escherichia coli (UPEC).
Researchers from the Universities of Bonn and Cologne observe how the danger sensor NLRP3 lengthens itself like a thread Redness, swelling, pain - these are signs of inflammation. It serves to protect the body from pathogens or foreign substances. Researchers from the Universities of Bonn and Cologne were able to show that inflammatory reactions of an important sensor protein proceed in a specific spatial direction.
A repair program for the heart
Following a heart attack, the human body is incapable of repairing lost tissue due to the heart's inability to generate new muscle. However, treatment with heart progenitor cells could result in the formation of functional heart cells at injured sites. This new therapeutic approach is introduced by an international team.
Following a heart attack, the human body is incapable of repairing lost tissue due to the heart's inability to generate new muscle. However, treatment with heart progenitor cells could result in the formation of functional heart cells at injured sites. This new therapeutic approach is introduced by an international team.
When genes mutate, this can lead to severe diseases of the human nervous system. Researchers at Leipzig University and the University of Würzburg have now used fruit flies to demonstrate how, apart from the negative effect, the mutation of a neuronal gene can have a positive effect - namely higher IQ in humans.
For more than ten years now, scientists have been discussing the so-called reproducibility crisis: often, scientific findings cannot be reproduced at a later time and/or in other laboratories, although the studies are carried out under highly standardised conditions. Thereby, standardisation includes for example the use of genetically identical animals, keeping the animals in identically equipped cages, and carrying out the experiments in always the same way.
Researchers discover molecular mechanisms of signal recognition of the neuropeptide system The human body consists of trillions of cells that constantly communicate with each other. A central role in this communication process is played by receptor proteins on the cell surface. Since they often serve as drug targets, they have been the subject of intensive research.
Mass fear decreases when measures to contain pandemics are effective
If infection numbers drop significantly over the course of a pandemic in response to policy measures, this lowers people's sense of fear and panic-related behaviour more strongly than the infection rates and the measures themselves.
If infection numbers drop significantly over the course of a pandemic in response to policy measures, this lowers people's sense of fear and panic-related behaviour more strongly than the infection rates and the measures themselves.
Coevolution between pathogens and host plant immune systems shapes a multifaceted network of interactions that remain phenotypically unrecognised and functionally elusive unless single players are depleted from the system. The maize-colonising fungus Ustilago maydis secretes a complex effector blend in order to suppress defence and redirect host metabolism in its favour.
Incorporating various minerals in collagen puts these composite materials under stress and makes them particularly hard and strong What engineers discovered only about 100 years ago has been used by nature for as long as vertebrates have existed. Just as steel wires under strain increase the fracture resistance of prestressed concrete, bones become particularly hard and strong because their collagen fibres are under stress due to embedded mineral nanoparticles.
Conventional vaccination campaign messages often miss their targets. A study in eight European countries shows that information on the benefits of vaccines can even reduce the willingness to get immunized. The researchers also looked into the factors that influenced the impact of messages, including low health literacy.
Liver fibrosis: the fatal signalling pathway
MHH research team clarifies how liver inflammation and scarring of liver tissue are connected At least five million people in Germany suffer from liver disease. Fibrosis, the pathological proliferation of connective tissue, plays an important role in many complications of chronic liver problems. Activated hepatic stellate cells (HSCs) are massively involved in this tissue remodelling.
MHH research team clarifies how liver inflammation and scarring of liver tissue are connected At least five million people in Germany suffer from liver disease. Fibrosis, the pathological proliferation of connective tissue, plays an important role in many complications of chronic liver problems. Activated hepatic stellate cells (HSCs) are massively involved in this tissue remodelling.
Rapid diagnosis instead of a long odyssey
MHH Human Genetics: Whole-genome sequencing to bring the cause of rare diseases in critically ill children to light at an early stage About four million people in Germany suffer from one of the many different rare diseases (SE) - especially seriously ill children who require intensive medical treatment.
MHH Human Genetics: Whole-genome sequencing to bring the cause of rare diseases in critically ill children to light at an early stage About four million people in Germany suffer from one of the many different rare diseases (SE) - especially seriously ill children who require intensive medical treatment.
Around 2 billion people worldwide are overweight. Obesity increases the risk of developing high blood pressure, heart attack or type 2 diabetes mellitus and can cause inflammation in the body that weakens the immune system through an accumulation of specific memory T and B cells. This process is called immune senescence, an age-related change in the immune system.
New discoveries about the origin of the brain’s immune system
Important immune cells in the brain's blood vessels do not mature until after birth What gets into the brain and what doesn't is strictly regulated. Researchers at the Faculty of Medicine at the University of Freiburg have now studied phagocytes that coat the blood vessels in the brain and reinforce the blood-brain barrier.
Important immune cells in the brain's blood vessels do not mature until after birth What gets into the brain and what doesn't is strictly regulated. Researchers at the Faculty of Medicine at the University of Freiburg have now studied phagocytes that coat the blood vessels in the brain and reinforce the blood-brain barrier.
