news 2021

Interdisciplinary research team from Göttingen University and Hannover Medical School are first to prove this directly An interdisciplinary research team from the University of Göttingen and Hannover Medical School (MHH) has detected significant changes in the heart muscle tissue of people who died from Covid-19.

When you enter the Institute of Neuroand Behavioural Biology at Badestraße 9 and go up the stairs on the left.. what you immediately see are the rows of pictures in the stairwell and the corridors. They look fascinating, in bright vibrant colours - but what they actually show is not apparent to the non-specialist at first glance.

A molecular switch influences addiction behaviour and determines how strong the response to addictive drugs is. A research team at Heidelberg University and the Sorbonne University in Paris (France) made the discovery in mice treated with cocaine. The researchers led by Hilmar Bading (Heidelberg) and Peter Vanhoutte (Paris) demonstrated that the protein Npas4 regulates the structure and function of nerve cells that control addiction behaviour in mice.

Interactive online platform uses satellite images to display status of European forests. The output is based on the greenness of trees. With the latest functionality, users can also view and download data for individual countries and selected time ranges to learn more about the condition of forests.

The skin is the largest organ of the human body. But what if the skin "disintegrates" at just the slightest touch? This is exactly what happens with Epidermolysis bullosa (EB), sometimes also known by the name 'butterfly disease'. This skin disease is based on genetic defects and, because there is no cure, it can be fatal, often even in young patients.

Göttingen researchers investigate the effect of certain enzymes in the healthy and diseased brain The brain is a remarkably complex and adaptable organ. However, adaptability decreases with age: as new connections between nerve cells in the brain form less easily, the brain's plasticity decreases. If there is an injury to the central nervous system such as after a stroke, the brain needs to compensate for this by reorganising itself.

Researchers aim at decoding tumour development in hereditary colon cancer using mathematical modelling of medical data A new interdisciplinary research project aims to uncover information that can help decode hereditary colon cancer with the aid of mathematical models. Mathematicians and tumour biologists of Heidelberg University, the Heidelberg Institute for Theoretical Studies, Heidelberg University Hospital, and the German Cancer Research Center are collaborating on the project.

A Cologne-based research team has discovered that the metabolism of mitochondria, the energy suppliers of cells, in macrophages coordinate wound healing to a significant degree. Macrophages belong to the white blood cells and are also known as scavenger cells.Sabine Eming and her collaborators and colleagues at the CECAD Cluster of Excellence for Aging Research at the University of Cologne showed that wound macrophages undergo different metabolic programs during tissue repair, which are required to support the successive phases for skin reconstruction after injury.

Study led by Göttingen and Syiah Kuala Universities finds Safe Childbirth Checklist contributes to improved maternal and neonatal healthcare Every year, 295,000 maternal deaths, 2 million stillbirths, and 2.5 million neonatal deaths occur worldwide. Improved quality of care could prevent the majority of those deaths.

Heidelberg researchers are working on a rapid process for 3D imaging of cells Viral pathogens like the SARS-CoV-2 coronavirus change the interior structure of the cells they infect. These changes occur at the level of individual cell components - the organelles - and can provide information on how viral diseases develop.

A team of biologists has identified that the pathogenic fungus Verticillium dahliae , responsible for wilt disease in many crops, secretes an 'effector' molecule to target the microbiome of plants to promote infection. The research was performed by the team of Alexander von Humboldt Professor Dr Bart Thomma at the University of Cologne (UoC) within the framework of the Cluster of Excellence on Plant Sciences (CEPLAS) in collaboration with the team of Dr Michael Seidl at the Theoretical Biology & Bioinformatics group of Utrecht University in the Netherlands.

Food supplements are available in a lot of places - in drugstores, health food shops, pharmacies and on the Internet - and the market is booming. Many of these products contain plant extracts whose ingredients are supposed to have healthy benefits - provided they do actually contain what they claim. Because nowhere near all of these so-called botanicals deliver what they promise.

11/29/2021 The cells of a certain tumour type, called neuroblastoma, divide very rapidly. This rapid division can have potentially fatal consequences for them. A new study shows how neuroblastoma cells deal with this dilemma. Neuroblastomas occur predominantly in children. A specific subset of these tumours is very aggressive and difficult to treat.

New link between diet, intestinal stem cells and disease discovered Obesity, diabetes and gastrointestinal cancer are frequently linked to an unhealthy diet. However, the molecular mechanisms responsible for this are hitherto not fully understood. Researchers at the Technical University of Munich and Helmholtz Munich have gained some new insights that help to better understand this connection.

The bodies of animals and humans are innervated by a network of nerve cells which are connected through long extensions. The nerve cells use these so-called axons and dendrites to communicate with one another. During early development, nerve cells grow a large number of axons and dendrites. To make the connections specific, redundant extensions are removed at a later stage in a process called "pruning".

Dr. Francesco Catania is head of the working group "Evolutionary Cell Biology" at the Institute for Evolution and Biodiversity at the University of Münster. His group uses bioinformatics and experimental approaches to investigate how the interaction of cells and organisms with their environment leads to the emergence of new properties.

International research team led by Göttingen University finds inadequate care Healthcare in lowand middle-income countries (LMICs) is poorly prepared for the increasing number of individuals with high cholesterol (i.e. hypercholesterolemia). A study on 35 LMICs shows that more than two-thirds of all people affected go without treatment.

If a family member falls ill with COVID-19, this has a particularly negative effect on young people from an economically disadvantaged and less educated background. These adolescents not only fall behind in school, their non-cognitive abilities also suffer: they are less prosocial than before. This means that they behave less generously, altruistically, and cooperatively.

Team including MHH and RESIST researchers has found starting point for therapy of diseases caused by herpes viruses A research team from the University of Lübeck, Hannover Medical School (MHH), CSSB Hamburg and the RESIST Cluster of Excellence has found a possible new starting point for the therapy of diseases triggered by herpes viruses.

Titin is a "titanically large" protein - the largest in the human body - which enables elastic movements of our muscles, including the heart. Mutations in the titin gene ( TTN ) that impair this function are the most frequent cause of a heart muscle disease known as dilated cardiomyopathy (DCM), which is characterized by a weak pump function.