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Life Sciences - Environment - 14.08.2020
Watching changes in plant metabolism - live
Watching changes in plant metabolism - live
Young thale cress seedling (Arabidopsis thaliana) with the fluorescent biosensor in its cells. The false colour image shows the redox status of the NAD pool in the cells and tissue. Rainbow scale from blue (oxidized NAD pool) to red (reduced NAD pool). Almost all life on Earth, in particular our food and our health, depend on metabolism in plants.

Life Sciences - 07.08.2020
Grow faster, die sooner
How growth rates influence the fitness of bacteria Bacteria are survival artists: When they get nutrition, they multiply rapidly, albeit they can also survive periods of hunger. But, when they grow too quickly, their ability to survive is hampered, as studies by a research team at the Technical University of Munich (TUM) on E. coli bacteria show.

Environment - Life Sciences - 29.07.2020
Smaller habitats worse than expected for biodiversity
Smaller habitats worse than expected for biodiversity
New international research breaks ground for the next generation of biodiversity forecasts No 131/2020 from Jul 29, 2020 Biodiversity's ongoing global decline has prompted policies to protect and restore habitats to minimize animal and plant extinctions. However, biodiversity forecasts used to inform these policies are usually based on assumptions of a simple theoretical model describing how the number of species changes with the amount of habitat.

Life Sciences - 27.07.2020
European and American maize: same same, but different
European and American maize: same same, but different
Adapting maize plants to climate change German researchers decoded the European maize genome. In comparison to North American maize lines, they discovered differences. For cultivation of maize in areas with low yields and for challenges imposed by the climate change these observations of the research team led by Klaus F.X. Mayer, head of the research group "Plant Genome and Systems Biology" at Helmholtz Zentrum München and Chris-Carolin Schön, Professor for Plant Breeding at the Technical University of Munich (TUM) might be of particular interest.

Life Sciences - Computer Science - 24.07.2020
More effective sharing of research data
More effective sharing of research data
National research data infrastructure: TUM involved in three consortia Genome sequencing produces immense quantities of data. The aim of the German Human Genome-Phenome Archive (GHGA) is to make these data available to science without violating the personality rights of patients. The GHGA will focus initially on data collections pertaining to cancer and rare genetic disorders.

Life Sciences - 20.07.2020
Reproductive genetics: New gene for male infertility discovered
Reproductive genetics: New gene for male infertility discovered
Impairment of sperm formation: male infertility is not only a concern for those affected but is also something which the working group led by Prof. Frank Tüttelmann is researching into. The Reproductive Genetics team at the Faculty of Medicine at the University of Münster is running a multitude of projects as it attempts to get to the bottom of further causes of male infertility.

Health - Life Sciences - 17.07.2020
A chemical tailor-made suit for Alzheimer's drugs
A chemical tailor-made suit for Alzheimer’s drugs
Research team from Göttingen and Halle develops new inhibitors for enzymes With over 1.2 million people affected in Germany alone and over 50 million people worldwide, Alzheimer's disease, also referred to simply as Alzheimer's, is one of the greatest medical and social challenges of our time.

Life Sciences - Health - 15.07.2020
Making balanced decisions
Making balanced decisions
Neuronal circuits in the brain 'sense' our inner state How decisions are made and how behavior is controlled is one of the most important questions in neuroscience. The neurotransmitter dopamine plays a central role in all of this. Scientists at the Technical University of Munich (TUM), together with researchers at the Max Planck Institute for Neurobiology, looked into the role that dopamine plays in the decision-making process and in controlling movement.

Life Sciences - Veterinary - 14.07.2020
Mystery about cause of genetic disease in horses
Research team led by Göttingen University questions link to warmblood fragile foal syndrome Warmblood fragile foal syndrome is a severe, usually fatal, genetic disease that manifests itself after birth in affected horses. Due to the defect, the connective tissue is unstable. Under force, for instance, the skin tears from the tissue underneath and the joints can suffer dislocation.

Life Sciences - Chemistry - 07.07.2020
Enzymes as double agents: new mechanism discovered in protein modification
Enzymes as double agents: new mechanism discovered in protein modification
Proteins are the workers in a cell and, as the “basic element of life”, are responsible for the most widely varying metabolic processes. In plants, for example, they take on an important function in photosynthesis. In order to be able to work purposefully, proteins change their chemical form after they have been produced in a cell - for example, through protein acetylation, when an acetyl group is transferred to the protein.

Life Sciences - Chemistry - 06.07.2020
How do bacteria build up natural products?
How do bacteria build up natural products?
X-ray structure analysis gives detailed insights into molecular factory The active agents of many drugs are natural products, so called because often only microorganisms are able to produce the complex structures. Similar to the production line in a factory, large enzyme complexes put these active agent molecules together.

Health - Life Sciences - 06.07.2020
Gut bacteria improve type 2 diabetes risk prediction
Gut bacteria improve type 2 diabetes risk prediction
Large-scale study with more than 4000 participants at ZIEL - Institute for Food & Health The composition and function of bacteria in the human intestine - the so-called gut microbiome - changes as the day progresses. This was established by researchers based in Freising at ZIEL - Institute for Food & Health of the Technical University of Munich (TUM) with one of the largest studies related to microbiomes and diabetes comprising more than 4000 participants.

Life Sciences - Agronomy / Food Science - 29.06.2020
Feeds of the Future
Feeds of the Future
University of Göttingen research team investigates the influence of insect and microalgae feeds on meat quality Worldwide there is a growing demand for animal products for human nutrition, despite vegan and vegetarian diets becoming more popular in Western countries. Changing diets necessitate a substantial amount of protein as an input for animal production.

Life Sciences - 16.06.2020
Hormone systems can still be adapted in adulthood
Hormone systems can still be adapted in adulthood
How do animals adapt their behaviour during life in order to assure survival and reproduction? This is a question of great interest for behavioural biologists worldwide. An essential step is to examine hormonal mechanisms which have a fundamental impact on the animal's behaviour and thus make adaptations to various social situations possible.

Life Sciences - Health - 10.06.2020
Researchers identify
Researchers identify "hot spots" for developing lymphatic vessels: Experiments on zebrafish
Experiments on zebrafish: fibroblasts produce important enzyme-processing proteins triggering growth in vessels / Study in "Nature Communications" When an embryo develops, a wide variety of proteins and enzymes trigger a series of biochemical reactions. The development of the lymphatic vasculature is crucially dependent on one specific protein - the growth factor VEGF-C.

Life Sciences - 05.06.2020
View into plant cells: A membrane protein is targeted to two locations
View into plant cells: A membrane protein is targeted to two locations
Metabolic processes are especially complex in plants due to their obligate sessile life style - which is why scientists discover more and more new and surprising connections that occur within their cells. An important metabolic route that has occupied plant scientists for decades is the so-called oxidative pentose-phosphate pathway by which carbohydrates are converted to reduction power.

Life Sciences - 05.06.2020
Protecting the Neuronal Architecture
Protecting nerve cells from losing their characteristic extensions, the dendrites, can reduce brain damage after a stroke. Neurobiologists from Heidelberg University have demonstrated this by means of research on a mouse model. The team, led by Hilmar Bading in cooperation with Junior Professor Dr Daniela Mauceri, is investigating the protection of neuronal architecture to develop new approaches to treating neurodegenerative diseases.

Life Sciences - 29.05.2020
Selectively Reactivating Nerve Cells to Retrieve a Memory
Selectively increasing the levels of a certain protein in nerve cells that play a key role in memory storage boosts memory performance, as demonstrated in experiments on mice by a group of scientists at Heidelberg University led by Dr Ana Oliveira. The responsible protein is Dnmt3a2 - a so-called epigenetic factor that chemically modifies the genome and thus influences memory processes.

Life Sciences - Health - 28.05.2020
Why developing nerve cells can take a wrong turn
Loss of ubiquitin-conjugating enzyme leads to impediment in growth of nerve cells / found between cellular machineries of protein degradation and regulation of the epigenetic landscape in human embryonic stem cells A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certai

Life Sciences - Chemistry - 26.05.2020
Triggered by light, a novel way to switch on an enzyme: Biotechnology
Triggered by light, a novel way to switch on an enzyme: Biotechnology
Enzymes: they are the central drivers for biochemical metabolic processes in every living cell, enabling reactions to take place efficiently. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as pharmaceutics. A topic that is currently being widely discussed is photoinduced catalysis, in which researchers harness the ability of nature to start biochemical reactions with the aid of light.
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