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Health - Life Sciences - 13.05.2020
A disease trigger for pancreatitis has been identified
A disease trigger for pancreatitis has been identified
A Calcium channel is involved in the development of pancreatitis One factor contributing to the development of pancreatitis lies in mutations within a cell membrane ion channel that is characterized by its specific permeability for calcium ions. This groundbreaking discovery was made by a research team at Technical University of Munich (TUM), in cooperation with other groups from Germany, Japan and France.

Health - Physics - 07.05.2020
New x-ray method for Corona diagnosis ready for patient testing
New x-ray method for Corona diagnosis ready for patient testing
Low-dose radiographs could reveal typical lung changes Researchers at the Technical University of Munich (TUM) have developed an innovative x-ray method for lung diagnostics, which they now plan to test in one of its first applications for diagnosis of the respiratory ailment Covid-19 caused by Coronavirus.

Health - 29.04.2020
Improving immunotherapy for cancer
Improving immunotherapy for cancer
Cause for the lack of immune defense against tumors discovered One of the reasons why cancer develops is because regulatory cells inhibit the body's immune defense. Researchers under the helm of the Technical University of Munich (TUM) have discovered a mechanism for identifying regulatory cells in tumor tissue that suppress an immune response.

Computer Science - Health - 24.04.2020
Encryption system for a secure contact tracing app
Coronavirus: Research team testing decentralized contact tracing In the fight against Covid-19, an interdisciplinary research team at the Technical University of Munich (TUM) has developed a model for a contact tracing app that protects personal data. The concept is based on an encryption process that prevents the temporary contact numbers (TCNs) of infected individuals from ending up on the phones of their contacts.

Health - Pharmacology - 24.04.2020
Parasite larvae could help fight allergies
New active ingredient against allergic asthma Our immune system protects us against pathogens. However, an excessive immune reaction can trigger allergies or chronic asthma. Scientists at the Technical University of Munich (TUM) and Helmholtz Zentrum München have discovered an active ingredient taken from the larvae of a worm parasite that could help diminish immune reactions.

Health - Mechanical Engineering - 23.04.2020
Computer model enables protective ventilation
Computer model enables protective ventilation
Computational model of the lung could significantly reduce the number of deaths from Covid-19 and ARDS The use of mechanical ventilation can save lives - and not just for COVID-19 patients who develop severe respiratory problems. But at the same time, the ventilation pressure puts immense stress on delicate lung tissue.

Health - Pharmacology - 21.04.2020
In-ear sensors to help in fight against COVID-19
In-ear sensors to help in fight against COVID-19
Can continuous monitoring provide protection for patients? A team at the Technical University of Munich (TUM) plans to use high-tech biometric sensors for 24-hour monitoring of COVID-19 patients in home isolation. The goal of the study is to find out whether rapid treatment in response to deteriorating vital signs can improve the chance of survival and ease the workload of intensive care units.

Health - 21.04.2020
Large Antibody Study at the Klinikum rechts der Isar
Large Antibody Study at the Klinikum rechts der Isar
Antibody tests against SARS-CoV-2 are designed to improve employee and patient safety One of the largest antibody studies against SARS-CoV-2 in Germany has begun at the university hospital Klinikum rechts der Isar at Technical University of Munich (TUM). The employee study is intended to provide data on the stability of antibodies over two years and thereby help in identifying starting points for the further improvement of protective measures for both employees and patients.

Health - 17.04.2020
Nasal smear as an allergy screening test
Detection of allergen-specific antibodies in nasal secretions In the world of allergy diagnostics, the familiar blood samples and unpleasant skin prick procedures for testing allergen tolerance may soon be a thing of the past. A team of researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum München has demonstrated that sufficient quantities of allergy antibodies for a diagnosis can be effectively measured in nasal secretions.

Life Sciences - Health - 15.04.2020
Preserving inflammation-free phases
Preserving inflammation-free phases
Early detection of Crohn's disease flare-ups leads to improved therapy options Crohn's disease is a chronic inflammatory disorder of the intestine that, in most cases, relapses episodically. As of now, there is no cure for this disease. A research group led by the Technical University of Munich (TUM) has discovered a marker at a microscopic level, which can be used to identify patients that show a high probability of suffering from an inflammation recurrence in the immediate future.

Pharmacology - Health - 26.03.2020
Medications against coronavirus in trial
Medications against coronavirus in trial
Clinical trials on Covid-19 at university hospital TUM Klinikum rechts der Isar The university hospital is participating in studies on new medications for people suffering from Covid-19. As part of a clinical study, patients can be treated with medications that are still under development. 50 patients infected with the novel Coronavirus are currently being treated at the university hospital TUM Klinikum rechts der Isar.

Life Sciences - Health - 25.03.2020
A new mechanism triggering cell death and inflammation: a left turn that kills
Z-form nucleic acids are double-stranded DNA and RNA molecules with an unusual left-handed double helix structure, as opposed to the classical right-handed Watson-Crick double helix. Z-nucleic acids were discovered more than 40 years ago, but their biological function has remained poorly understood.

Health - 20.03.2020
Health forums: Style of language influences credibility and trust
Health forums: Style of language influences credibility and trust
More and more, people are using internet forums as first place to look for information on health issues. However, the scientific medical information being provided there is often so complex that laypeople are barely able to form considered judgements on the content of much of the advice. One criterion which users apply instead in evaluating the information is the style of the language used.

Health - Life Sciences - 17.03.2020
Blocking sugar structures on viruses and tumor cells
Blocking sugar structures on viruses and tumor cells
Coronavirus: University operations limited +++ make use of online services +++ many staff working from home +++ www.tum.de/corona Artificial sugar-binding protein may inhibit cell growth During a viral infection, viruses enter the body and multiply in its cells. Viruses often specifically attach themselves to the sugar structures of the host cells, or present characteristic sugar structures on their surface themselves.

Life Sciences - Health - 13.03.2020
Analysis of whole brain vasculature
Analysis of whole brain vasculature
Coronavirus: University operations limited +++ make use of online services +++ many staff working from home Biochemical methods and AI show even the finest capillaries Diseases of the brain are often associated with typical vascular changes. Now, scientists at LMU University Hospital Munich, Helmholtz Zentrum München and at the Technical University of Munich (TUM) have come up with a technique for visualising the structures of all the brain's blood vessels - right down to the finest capillaries - including any pathological changes.

Health - 10.03.2020
Fatal overproduction of antibodies
Fatal overproduction of antibodies
Mutations in plasma cells play a key role in light chain amyloidosis Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains. These associate to fibrils and deposit in organs.

Health - 05.03.2020
Towards improved cochlear implants
Towards improved cochlear implants
Computer model shows neuronal activation patterns in the inner ear Research towards improved cochlear implants Cochlear implants restore hearing in deaf people to an amazingly high level. In order to optimize such implants, researchers at the Technical University of Munich (TUM) have developed a computer model which predicts the neuronal activation patterns that the implant creates in the auditory nerve fibers.

Life Sciences - Health - 05.02.2020
The invisibility cloak of a fungus
The invisibility cloak of a fungus
While viruses and bacteria regularly manage to infect the human organism, fungi only very rarely succeed. The reason for this is that the human immune system can recognize them very easily because their cells are surrounded by a solid cell wall of chitin and other complex sugars. Chitin is, so to speak, the alarm signal for our immune system, to which it reacts with a whole arsenal of defensive weapons.

Pharmacology - Health - 04.02.2020
Hepatitis B: New therapeutic approach
Hepatitis B: New therapeutic approach
Therapeutic vaccination may help to cure chronic hepatitis B infection Researchers at Technical University of Munich (TUM), Helmholtz Zentrum München and the German Center for Infection Research (DZIF) have developed a novel therapeutic approach to cure chronic hepatitis B. The scientists found that the large amount of hepatitis B virus proteins expressed in the liver prevents the body's immune system to defeat the virus.

Health - Pharmacology - 04.02.2020
What can be done to combat the third leading cause of death worldwide?
Freie Universität Berlin participates in international research project to develop new therapies against antibiotic-resistant pathogens of pneumonia / Funded with 10 million euros from the European Union No 025/2020 from Feb 04, 2020 Scientists from eleven European research institutions, including the Institute of Pharmacy at Freie Universität Berlin, are jointly looking for new ways to combat antibiotic-resistant pathogens.

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