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Health - Economics / Business - 28.07.2020
How will the population accept COVID-19 tracing apps?
How will the population accept COVID-19 tracing apps?
Research team led by the University of Göttingen analyses design and communication strategies for mass acceptance Coronavirus tracing applications for the detection of infection chains are currently being developed and made available across the world. Such contact-tracing apps are a central component of national strategies for relaxing restrictions.

Environment - Health - 21.07.2020
Cavefish have fewer cells of the innate immune system
Cavefish have fewer cells of the innate immune system
Adaptation of cavefish to low-parasite environment may provide autoimmune disease insight / Study published in "Nature Ecology & Evolution" Cavefish are small, live in tucked away places humans rarely go, and they're common enough that you can find them on every continent except Antarctica. But they also have another characteristic that seems surprising at first glance: They can tell researchers something about the occurrence of autoimmune diseases in humans.

Health - Life Sciences - 17.07.2020
A chemical tailor-made suit for Alzheimer's drugs
A chemical tailor-made suit for Alzheimer’s drugs
Research team from Göttingen and Halle develops new inhibitors for enzymes With over 1.2 million people affected in Germany alone and over 50 million people worldwide, Alzheimer's disease, also referred to simply as Alzheimer's, is one of the greatest medical and social challenges of our time.

Life Sciences - Health - 15.07.2020
Making balanced decisions
Making balanced decisions
Neuronal circuits in the brain 'sense' our inner state How decisions are made and how behavior is controlled is one of the most important questions in neuroscience. The neurotransmitter dopamine plays a central role in all of this. Scientists at the Technical University of Munich (TUM), together with researchers at the Max Planck Institute for Neurobiology, looked into the role that dopamine plays in the decision-making process and in controlling movement.

Health - Life Sciences - 06.07.2020
Gut bacteria improve type 2 diabetes risk prediction
Gut bacteria improve type 2 diabetes risk prediction
Large-scale study with more than 4000 participants at ZIEL - Institute for Food & Health The composition and function of bacteria in the human intestine - the so-called gut microbiome - changes as the day progresses. This was established by researchers based in Freising at ZIEL - Institute for Food & Health of the Technical University of Munich (TUM) with one of the largest studies related to microbiomes and diabetes comprising more than 4000 participants.

Health - Pharmacology - 23.06.2020
The tricks of the immune system
The tricks of the immune system
How the T-cell response changes in chronic virus infections "The Covid-19 pandemic clearly demonstrates the importance of understanding how the immune system reacts to virus infections," says Dr. Kilian Schober. Together with an interdisciplinary team of researchers from Medicine, Biology and Bioinformatics, he is investigating how important agents in the body's immune system known as T lymphocytes or T cells react when a virus invades the organism and how the immune response changes when the infection becomes chronic.

Health - Physics - 11.06.2020
New Strategies for Virus Inhibition
Highly flexible or spiky nanosystems by Berlin researchers open the door for new antiviral options against influenza viruses No 098/2020 from Jun 11, 2020 Berlin researchers have applied two new strategies based on multivalent nanosystems for making influenza A viruses (IAV) innocuous. The decisive factor in the development of these new strategies against influenza was the cooperation between scientists from different disciplines - chemistry, physics, virology, and imaging - the collaborative partners of Freie Universität Berlin, Humboldt University Berlin, and the Robert Koch Institute.

Life Sciences - Health - 10.06.2020
Researchers identify
Researchers identify "hot spots" for developing lymphatic vessels: Experiments on zebrafish
Experiments on zebrafish: fibroblasts produce important enzyme-processing proteins triggering growth in vessels / Study in "Nature Communications" When an embryo develops, a wide variety of proteins and enzymes trigger a series of biochemical reactions. The development of the lymphatic vasculature is crucially dependent on one specific protein - the growth factor VEGF-C.

Pharmacology - Health - 05.06.2020
A newly discovered disease may lead to better treatment of cystic fibrosis
A newly discovered disease may lead to better treatment of cystic fibrosis
Cystic fibrosis is the most frequent severe inherited disorder worldwide. Every year, hundreds of families are confronted with this diagnosis - and to date, there is no cure for this disease that mainly affects the respiratory system. Besides supportive treatments, a lung transplant is often the only option to save a patient's live.

Health - Pharmacology - 03.06.2020
Remdesivir effective against Covid-19 even after short treatment periods
Remdesivir effective against Covid-19 even after short treatment periods
Comparable clinical results after five and ten days of treatment In an international study, scientists from eight countries have investigated the use of the medication Remdesivir in the treatment of Covid-19. One result of the study, which included the participation of the Technical University of Munich's university hospital TUM Klinikum rechts der Isar: The changes in the clinical condition of patients treated for five days were comparable to the changes in patients treated for a period of ten days.

Health - Physics - 29.05.2020
Three Successful Funding Bids for Collaborative Research Centres
Heidelberg University succeeded in gaining funding from the German Research Foundation (DFG) in the latest approval round for three, internationally visible collaborative research centres. In physics, the collaborative research centre (CRC) studying isolated quantum systems in experimental and theoretical investigations will continue its work in the second funding period (CRC 1225).

Life Sciences - Health - 28.05.2020
Why developing nerve cells can take a wrong turn
Loss of ubiquitin-conjugating enzyme leads to impediment in growth of nerve cells / found between cellular machineries of protein degradation and regulation of the epigenetic landscape in human embryonic stem cells A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certai

Health - Life Sciences - 26.05.2020
High-resolution 3D view inside tumors
High-resolution 3D view inside tumors
Breast cancer is the most common cancer in women. But individual tumors can vary significantly, presenting different spatial patterns within their mass. Researchers at the Technical University of Munich (TUM) and Helmholtz Zentrum München have now succeeded in visualizing spatial changes within tumors by means of optoacoustics.

Health - Life Sciences - 13.05.2020
A disease trigger for pancreatitis has been identified
A disease trigger for pancreatitis has been identified
One factor contributing to the development of pancreatitis lies in mutations within a cell membrane ion channel that is characterized by its specific permeability for calcium ions. This groundbreaking discovery was made by a research team at Technical University of Munich (TUM), in cooperation with other groups from Germany, Japan and France.

Health - Physics - 07.05.2020
New x-ray method for Corona diagnosis ready for patient testing
New x-ray method for Corona diagnosis ready for patient testing
Researchers at the Technical University of Munich (TUM) have developed an innovative x-ray method for lung diagnostics, which they now plan to test in one of its first applications for diagnosis of the respiratory ailment Covid-19 caused by Coronavirus. The method could clearly identify abnormalities typical of the illness and involves a significantly lower radiation dose than the computed tomography methods currently in use.

Health - 29.04.2020
Improving immunotherapy for cancer
Improving immunotherapy for cancer
One of the reasons why cancer develops is because regulatory cells inhibit the body's immune defense. Researchers under the helm of the Technical University of Munich (TUM) have discovered a mechanism for identifying regulatory cells in tumor tissue that suppress an immune response. Their findings may contribute to improving diagnosis and immunotherapy of cancer.

Computer Science - Health - 24.04.2020
Encryption system for a secure contact tracing app
In the fight against Covid-19, an interdisciplinary research team at the Technical University of Munich (TUM) has developed a model for a contact tracing app that protects personal data. The concept is based on an encryption process that prevents the temporary contact numbers (TCNs) of infected individuals from ending up on the phones of their contacts.

Health - Pharmacology - 24.04.2020
Parasite larvae could help fight allergies
Our immune system protects us against pathogens. However, an excessive immune reaction can trigger allergies or chronic asthma. Scientists at the Technical University of Munich (TUM) and Helmholtz Zentrum München have discovered an active ingredient taken from the larvae of a worm parasite that could help diminish immune reactions.

Health - Mechanical Engineering - 23.04.2020
Computer model enables protective ventilation
Computer model enables protective ventilation
Computational model of the lung could significantly reduce the number of deaths from Covid-19 and ARDS Computer model enables protective ventilation The use of mechanical ventilation can save lives - and not just for COVID-19 patients who develop severe respiratory problems. But at the same time, the ventilation pressure puts immense stress on delicate lung tissue.

Health - Pharmacology - 21.04.2020
In-ear sensors to help in fight against COVID-19
In-ear sensors to help in fight against COVID-19
A team at the Technical University of Munich (TUM) plans to use high-tech biometric sensors for 24-hour monitoring of COVID-19 patients in home isolation. The goal of the study is to find out whether rapid treatment in response to deteriorating vital signs can improve the chance of survival and ease the workload of intensive care units.

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