Coupled Proteins

The image portrays which G-proteins bind to particular G-protein coupled recepto
The image portrays which G-proteins bind to particular G-protein coupled receptors (GPCRs) and in turn how these are related to signalling events. | Thomas Splettstoesser

Researchers from Heidelberg University and Sendai University in Japan used new biotechnological methods to study how human cells react to and further process external signals. They focussed on the interaction between so-called G-proteins - the "mediators" of signal transmission - and the receptors known as GPCRs, which trigger signal processes. The researchers not only gained a better understanding of GPCR-G-protein interactions; they are now able to predict their functions better than before.

All living systems react to external signals from the environment. In humans and other animals, these signals are primarily detected and processed with biological receptors in the cell membrane that are coupled to the G-protein. ...

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