news 2015
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Scientists reach for the limits: Get the new issue of the Technologist magazine
Giant waste bins
The "dark matter" in the protein universe
Mini-intestine grown in a test tube
Possible Reasons Found for Failure of Alzheimer’s Treatment
Protein Repairs Nerve Cell Damage
Novel high-throughput approach for the analysis of cancer genes
New state-of-the-art compact X-ray source
Alzheimer’s disease: Plaques impair memory formation during sleep
New field of application for versatile helper
Cell marker enables prognosis about the course of infections
25 million euros for multiple sclerosis research
Pancreatic cancer: TUM researchers develop a new therapy concept
Health
Results 1 - 20 of 26.
Life Sciences - Health - 21.12.2015
Protein That Boosts Memory Identified
Increasing the level of a certain DNA-modified enzyme in the brain significantly improves cognitive ability. The discovery was made by the research team led by Hilmar Bading at the Interdisciplinary Center for Neurosciences of Heidelberg University. Mouse experiments showed that the Dnmt3a2 protein can boost memory performance in the animals.
Health - Life Sciences - 18.12.2015
Drying out the reservoir
A German-Dutch team has succeeded in immunizing dromedaries against the MERS virus. As the camels appear to be the major reservoir of the virus, the vaccine should also reduce the risk of future outbreaks of the disease in humans. Research on MERS has identified camels as the primary source of human infections, although the virus causes only mild symptoms in that host.
Health - Life Sciences - 18.12.2015
Insensitive irritable bowel syndrome
For the first time, biopsies of patients with irritable bowel syndrome have shown that the nerves in their gut wall respond poorly to a cocktail of inflammatory substances. This refutes the previous theory that patients with irritable bowel syndrome have an overly sensitive gut. The new study by scientists of the Technical University of Munich (TUM) was carried out in collaboration with several German hospitals.
Life Sciences - Health - 06.12.2015

Six researchers from Europe reveal just how far they go to discover some of nature's deepest secrets or test novel technologies. Among them: Prof. Elisa Resconi, experimental physicist from TUM. Find this and more exciting stories about science and innovation from Europe in the new issue of the Technologist magazine.
Life Sciences - Health - 30.11.2015

If rubbish is too big and unwieldy for normal household waste, its removal becomes the job of specialized experts. Researchers from the Technical University of Munich (TUM) have now discovered, in cooperation with colleagues from the UK, how large, fused cells help our body to deal with bulky items that may otherwise obstruct normal physiological processes.
Life Sciences - Health - 26.11.2015
Looking on the brighter side
The effect of a widespread genetic variant that increases the risk for childhood asthma can be neutralized. A new study shows that young infants are particularly responsive to the positive influence of exposure to farm dust. LMU asthma researchers have shown, for the first time, that specific environmental influences can neutralize the effect of a prevalent genetic variant that increases risk for childhood asthma.
Life Sciences - Health - 25.11.2015

Whether in the form of antibodies, enzymes or carriers: proteins play a crucial role in biology. While researchers have been able to at least partially determine the three-dimensional structure of many proteins, the structures of many other protein building blocks and even entire protein molecules remain as yet unknown.
Linguistics / Literature - Health - 20.11.2015
Language Use in Later Life
Research Workshop of Université catholique de Louvain and Freie Universität Berlin from December 7 to 9, 2015 How does language use change with increasing age? What can psychologists learn from linguists and vice versa? And how can the findings of linguistic research be useful for health care workers, care givers, relatives, and senior citizens themselves? These and other issues will be addressed by the participants of a research workshop that will take place from December 7 to 9, 2015, at Universität Louvain (UCL).
Health - Agronomy / Food Science - 19.11.2015

The ability to grow three-dimensional precursors of an organ from stem cells in a Petri dish has brought about a revolution in the field of biomedicine. But exactly what can be researched on such an organoid in vitro? A team from the Technical University of Munich (TUM) has now shown for the first time how artificially grown mini-intestines can be used in nutritional and diabetic research.
Life Sciences - Health - 09.11.2015

Agglutinated proteins in the brain, known as amyloid-? plaques, are a key characteristic of Alzheimer's. One treatment option uses special antibodies to break down these plaques. This approach yielded good results in the animal model, but for reasons that are not yet clear, it has so far been unsuccessful in patient studies.
Life Sciences - Health - 04.11.2015

In laboratory experiments on the basic mechanisms that cause Alzheimer's dementia, an international research team led by Heidelberg neurobiologist Ulrike Müller and a team of French scientists have succeeded in largely "repairing" the nerve cell damage typical in this disease. The researchers took a closer look at a key protein in Alzheimer's pathogenisis, APP, and one of its cleavage products APPs'.
Health - Life Sciences - 30.10.2015

An international team of scientists, led by Prof. Roland Rad at the University Hospital Klinikum rechts der Isar of Technical University of Munich (TUM), has developed a multiplexed screening approach together with colleagues of the Wellcome Trust Sanger Institute. The method can be used to mutate simultaneously many different genes in adult mice.
Health - Life Sciences - 29.10.2015

For some years now it has been possible to generate high-brilliance X-rays using ring-shaped particle accelerators (synchrotron sources). However, such installations are several hundred meters in diameter and cost billions of euros. The world's first mini synchrotron was inaugurated today at Technical University of Munich (TUM).
Health - Life Sciences - 27.10.2015
Lifestyle Change Could Reduce Risk of Alzheimer’s
Changes in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University's Network Aging Research (NAR), who examined the data from two independent epidemiological studies. Carriers of the ApoE4 genetic risk factor for Alzheimer's may be able to reduce their increased risk of cognitive decline by reducing their cholesterol level, especially if they also suffer from cardiovascular disease.
Life Sciences - Health - 22.10.2015

Alzheimer's patients frequently suffer from sleep disorders, mostly even before they become forgetful. Furthermore, it is known that sleep plays a very important role in memory formation. Researchers from the Technical University of Munich (TUM) have now been able to show for the first time how the pathological changes in the brain act on the information-storing processes during sleep.
Life Sciences - Health - 12.10.2015

In Alzheimer's disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum München have now uncovered how the protein interacts with other proteins.
Health - Life Sciences - 12.10.2015
Jamming the signal
LMU researchers have developed a short peptide that inhibits the activation of a signal pathway in monocytes that enables monocytes to adhere stick to endothelial cells and penetrate sites of acute inflammation. The image depicts the binding of the SKY peptide to CCL5 (green), which inhibits docking of HNP1 and thus prevents the formation of the HNP1-CCL5 heteromer.
Health - Chemistry - 01.10.2015

When a pathogen invades the body, specific cells in the human immune system are ready to take immediate action in order to destroy it. The molecular characteristics of these killer cells were unknown until recently. Now, for the first time, a team from the Technical University of Munich (TUM) has managed to create a molecular profile of the protective cells.
Health - Life Sciences - 23.09.2015

As one of the central fields of medical research at the Technical University of Munich (TUM), neuroscience is to gain a new research center for multiple sclerosis (MS). In Germany alone, some 200,000 people are affected by this as yet incurable disease, the cause of which remains unknown. Researchers at the TUM Klinikum rechts der Isar will now focus on MS and link clinical aspects of the disease with basic research.
Health - Life Sciences - 23.09.2015

Pancreatic cancer is one of the most aggressive forms of cancer and one of the most difficult to treat. Its high resistance to treatment is a major problem, particularly in the advanced stages. Researchers at Klinikum rechts der Isar University Hospital of the Technical University of Munich (TUM) have joined forces with a team from Stanford University to investigate a conceptually new approach to therapy which primarily takes epigenetic mechanisms into consideration.
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