Utilizing the tumor’s appetite for sugar

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T-cell lymphomas are particularly aggressive. A team led by  Jürgen Ruland has d
T-cell lymphomas are particularly aggressive. A team led by Jürgen Ruland has discovered how they grow so quickly and how this process can be stopped.




Growth mechanism in T cell lymphomas decoded

A team from the Technical University of Munich (TUM) has decoded the factor that makes T cell lymphomas grow comparatively rapidly: A missing "emergency shut-off switch" results in the lymphomas processing particularly large amounts of sugar and triggers other processes as well. Medications for other types of cancer can stop this process, causing the tumor cells to die off. The process is to be verified in clinical studies in the near future.

T cell lymphomas are a subgroup of tumors which are especially aggressive and difficult to treat, in part because much remains as yet unknown about the molecular processes involved in this type of cancer. A team led by Prof. ...
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