A picture of immune cells in a lymph node. Resident cells are marked in red, circulating ones in cyan. What is striking is that regulatory T cells (outlined in yellow) are found in both forms. (Image: Milas Ugur/JMU)Contrary to prior belief, certain T-cells remain in lymph nodes for a long time and store information about immune reactions there. That’s been discovered by researchers at the University of Würzburg and the RWTH Aachen.
The immune system is fast when it comes to fighting viruses, bacteria and other pathogens. But it also has to know when not to attack - for example, harmless substances such as pollen or house dust, which otherwise trigger allergic reactions. Regulatory T cells (Tregs) in the lymph nodes play a key role here, suppressing excessive or misdirected immune responses there. ...
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