Fluorinated sugar molecules as vaccine leads against meningitis B and C

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Research team mimics natural molecular structures / New possibility for vaccine development

Chemists from the University of Münster and the Max Planck Institute (MPI) of Co
Chemists from the University of Münster and the Max Planck Institute (MPI) of Colloids and Interfaces in Potsdam have now developed a combined vaccine lead from synthetic fluorinated sugar molecules that is effective against meningococci B and C simultaneously. © AK Gilmour
Meningococci (Neisseria meningitidis) are disease-causing bacteria that cause life-threatening meningitis, or blood poisoning (septicaemia). There are a number of meningococcal variants worldwide, known as serogroups, and in Germany the Standing Committee on Vaccination (STIKO) recommends immunisation against serogroups B and C in children. A team from the University of Münster (led by Ryan Gilmour) and the Max Planck Institute (MPI) of Colloids and Interfaces in Potsdam (led by Peter H. Seeberger) has now developed a combined vaccine lead from synthetic fluorinated sugar molecules that is effective against both strains simultaneously. ...
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