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Using the largest dataset of human fossils from Ice Age Europe to date, an international research team shows how prehistoric hunter-gatherers coped with climate change in the period between 47,000 and 7,000 years ago.

An international research team has sequenced the largest genomes of all'animals - those of lungfish. The data will help to find out how the ancestors of land vertebrates managed to conquer the mainland. Let's travel back through time to the late Devonian period, around 380 to 360 million years in the past.

Aerobic methane-oxidizing bacteria are also permanently active in oxygen-free water Methane-oxidizing bacteria could play a greater role than previously thought in preventing the release of climate-damaging methane from lakes, researchers from Bremen report. They also show who is behind the process and how it works.

Memory loss, confusion, speech problems - Alzheimer's disease is the most common cause of dementia, affecting about 35 million people worldwide, and the number is growing. The protein amyloid beta, which occurs naturally in the brain, plays a central role in the disease: It accumulates in patients in insoluble clumps that form plaques between neurons in the brain, damaging them.

Prerequisite for protective effects of fasting is an increase in the concentration of the endogenous substance spermidine in the organism / international study involving the team of Stephan Sigrist from Freie Universität According to the results of an international study involving the Freie Universität Berlin, fasting can prolong life and increase the health span.

The protective effects of fasting depend on an increase in the concentration of spermidine, according to an international study involving a team led by Professor Stephan Sigrist from Freie Universität Berlin According to the findings of an international study, fasting can extend people's lifespan and increase overall health.

University of Bonn researchers are studying the lifespan and growth patterns of early mammals What distinguishes the growth and development patterns of early mammals of the Jurassic period? This is the question jointly investigated by researchers of Queen Mary University of London and the University of Bonn.

Mast cells trap and use living neutrophils during allergic reactions Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation.

The brain is constantly storing new experiences that it has to integrate into the jumble of existing memories. Surprisingly, it does not overwrite previous memory traces in the process. The first day of school: entering the classroom for the first time, the excited feeling in your stomach and the joy of having a school bag - these are all typical examples of memories from our episodic memory.

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation. Now, researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the University of Münster have discovered a hidden talent of mast cells: they can capture and use another type of immune cell called neutrophils.

Immune cells in the brain form bridges to nerve cells and protect against neurodegenerative diseases When nerve cells in the brain die, diseases such as Alzheimer's and Parkinson's develop. To protect these cells, there are immune cells in the brain known as microglia. A study has now shown that microglia form tiny tubes, so-called -tunnelling nanotubes-, and thus connect directly to the nerve cells.

In a collaborative project between the Faculty of Veterinary Medicine and the Interdisciplinary Centre for Bioinformatics (IZBI) at Leipzig University, changes in gene expression in sebaceous glands have been spatially mapped for the first time. The study documents at high resolution changes in gene expression in the course of sebum synthesis and identifies new candidates for the modulation of sebum production.

We all know what it's like when the penny suddenly drops. Animals too experience such moments of insight. They could prove useful for research, according to Ekrem Dere. For generations, researchers have been pondering the question of how and where consciousness is formed in the brain. Professor Ekrem Dere from Ruhr University Bochum, Germany, proposes a new approach to researching conscious cognitive information processing.

Bonn researchers confirm three other genes for increased risk in addition to the known TLR7 gene Whether or not a person becomes seriously ill with COVID-19 depends, among other things, on genetic factors. With this in mind, researchers from the University Hospital Bonn (UKB) and the University of Bonn, in cooperation with other research teams from Germany, the Netherlands, Spain and Italy, investigated a particularly large group of affected individuals.

Researchers at the University of Göttingen investigate consumer acceptance   Companies and institutes are currently working on biotechnological processes for the production of dairy products without the use of cows: In so-called precision fermentation, egg and milk proteins are produced with the help of bacteria, yeasts or other fungi.

Freiburg researchers develop new formal description of internal world models, thereby enabling interdisciplinary research A team of scientists led by Ilka Diester , Professor of Optophysiology and spokesperson of the BrainLinks-BrainTools research centre at the University of Freiburg, has developed a formal description of internal world models and published it in the journal Neuron .

Bonn researchers solve the hidden mystery of the role of astrocytes for learning processes and memory in the brain Star-shaped glial cells, so-called astrocytes, are more than just a supporting cell of the brain. They are actively involved in learning processes and interact with the nerve cells. But what exactly is it that astrocytes do? Researchers at the University Hospital Bonn (UKB) and the University of Bonn are using a biophysical model to clarify how astrocytes interact with nerve cells to regulate rapid adaptation to new information.

A team at the Helmholtz Centre for Infection Research in Würzburg, Germany, led by RNA expert Chase Beisel, has developed a new technology for the precise detection of RNA using DNA-cutting Cas12 nucleases. CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

International team of evolutionary biologists investigate genomic underpinnings for the adaptive potential of spoonworts Plant cold specialists like the spoonworts have adapted well to the cold climates of the Ice Ages. As cold and warm periods alternated, they developed a number of species that also resulted in a proliferation of the genome.

Researchers have developed the first cell-free system in which genetic information and metabolism work together Metabolic processes outside living cells only continue as long as they are supplied with building blocks from the outside. A team of Max Planck researchers led by Tobias Erb has now developed the first in vitro system inspired by nature that couples genetics and metabolism and can drive itself.