Mast cells trap and use living neutrophils during allergic reactions
This scanning electron microscopy image captures the moment where degranulating mast cells (sepia) attract and start to incorporate living neutrophils (cyan). Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation. Now, researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the University of Münster have discovered a hidden talent of mast cells: they can capture and use another type of immune cell called neutrophils. This surprising discovery sheds new light on how our immune system works, particularly during allergic reactions.
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