Cell atlas of regenerating liver

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Map of liver cells (UMAP plot) of healthy (n = 3), regenerating (n = 6) and embo
Map of liver cells (UMAP plot) of healthy (n = 3), regenerating (n = 6) and embolized (n = 6) liver samples, coloured by condition. Modified according to Fig. 2c from the original publication.

The liver has a remarkable ability to regenerate. This property is crucial for maintaining organ function and recovery after injury or surgery. Scientists from the University of Leipzig Medical Center, the Max Planck Institute for Evolutionary Anthropology, TU Dresden and ETH Zurich have used clinical samples to investigate how cell types in the liver change before and after regeneration. They have created a cell atlas from the recent study data published in the renowned journal Nature Communications.

In clinical practice, liver regeneration is triggered by an established procedure called portal vein embolization (PVE). ...

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