Tracing the Evolution of the ’Little Brain’

Heidelberg scientists unveil genetic programmes controlling the development of cellular diversity in the cerebellum of humans and other mammals

Genetic maps of the development of cells in the cerebella of human, mouse and op
Genetic maps of the development of cells in the cerebella of human, mouse and opossum shed light on ancestral and species-specific cellular and molecular characteristics of cerebellum development. | © Mari Sepp

The evolution of higher cognitive functions in human beings has so far mostly been linked to the expansion of the neocortex - a region of the brain that is responsible, inter alia, for conscious thought, movement and sensory perception. Researchers are increasingly realising, however, that the "little brain" or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans, explains Henrik Kaessmann from the Center for Molecular Biology of Heidelberg University. ...

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