The three reactants and their linkage: ketyl-type radical on the left, 1,3-diene on the center, and the nucleophile sulfinate on the right. The reactive atoms and the bond that are being formed are highlighted in yellow (ketyl carbon and first C-C bond) and orange (Sulfur nucleophile atom and second C-S bond). The catalytically active palladium complex, with the palladium center highlighted in orange, is visible in the background.
More environmentally friendly approach produces complex molecular structures in one step / Ketyl radicals "tamed" by photocatalysis A more sustainable use of chemical resources is part of the United Nations' Agenda 2030. Synthetic chemists are therefore working to design and carry out efficient syntheses. Within the synthetic organic chemist's arsenal, processes that link several molecules (coupling partners) in a single step - so-called multi-component reactions (MCRs) - play a central role. These are considered sustainable and environmentally friendly technologies for the rapid production of complex structures and drugs in a single reaction step.
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