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Results 241 - 260 of 363.
A clinical trial will investigate the drug's efficacy in dementia patients. A common feature of many neurodegenerative diseases are pathological protein deposits in the brain. These protein aggregates cause nerve cells to die and, as a result, entire brain areas to shrink, which manifests itself in affected individuals as progressive dementia.
Intervention in RNA switches off "cancer genes" / American-German team publishes study in "Nature" If the regulation of cell growth and division gets out of control, cancer is a possible consequence. The gene "MYC", for example, plays an important role in controlling cell growth in humans. If it no longer functions properly, cells grow uncontrollably.
Research team at Göttingen University analyse data from burial sites spanning nearly 4,000 years People tend to think that the idea that biological sex is linked with one-s role in society belongs in the past. But was it even the case in prehistory? Archaeologists at the University of Göttingen have investigated the representation of gender in Neolithic and Bronze Age graves (around 5500 BC to 1200 BC), in order to understand if the idea of gender in prehistoric Europe was really as -binary- as might be expected.
Sky rock testifies to intense collisions in early solar system A suspected meteorite find at the end of April in Elmshorn in Schleswig-Holstein has now been confirmed: Scientists from Münster and Dresden have analyzed the find and determined that the rock is a so-called common type H chondrite. This is a group of meteorites that have a particularly high proportion of metal.
Resarchers have found new possibilities for targeting cancer genes' RNA with nature-inspired compounds The cancer gene MYC drives unrestrained growth of most human cancers. It has been called the "Mount Everest" of cancer research because of the difficulty of designing medications that can disable it, and the expectation that an effective MYC drug could help so many cancer patients.
Astronomers at the University of Potsdam have succeeded in making one of the world's first brightness measurements of the supernova SN2023ixf in the constellation Ursa Major, which was discovered only on Friday evening. It is the brightest detected outburst in more than ten years in the galaxy Messier 101.
Newly discovered signalling pathway specifically protects the stem cells in the plant root from salt stress A high content of sodium-containing salts in the soil is a problem for many plants: as a result, they grow less well, or not at all. Soil salinisation is seen as one of the greatest threats to being able to feed the world's population because it makes soils increasingly infertile, especially in dry regions.
Researchers make visible how a nanomachine takes care of cleaning up in the cell To keep our body's cells from overflowing with waste and to keep them healthy, the waste inside them is constantly being disposed of. This cleaning process is called autophagy. Scientists have now, for the first time, recreated in the laboratory the complex nanomachine that starts this process and found that it works quite differently from other cellular machines.
The Collaborative Research Centre ToCoTronics in condensed matter physics will be extended for four more years. The German Research Foundation is funding it with 12 million euros. Topological materials are intensively investigated in the world. This boom started at Julius-Maximilians-Universität (JMU) Würzburg, where the physics professor Laurens Molenkamp realized the first topological insulator in 2007.
News from Studying proteins with novel methods is Dr Matthias Elgeti's speciality. An EPR spectrometer is helping him to study the structure and dynamics of G protein-coupled receptors (GPCRs). His work is concerned with the side effects of drugs and the regulation of bodily functions such as hunger.
Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. An international team of plant biologists has demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to research team leader Alexis Maizel of the Centre for Organismal Studies at Heidelberg University.
A new look at the brain's immune system Microglia cells, which play a major role in the immune system of the brain, are difficult to study. Researchers have now succeeded in modelling the development of the brain and its immune system using organoids. With these miniature models of groups of brain cells, they have investigated changes associated with a certain type of autism spectrum disorder.
Sustainability research: Wolfram Barfuss appointed new Argelander professor at the University of Bonn How can people work together to forge new, environmentally sustainable paths in a complex system? This is the question being tackled by Jun. Wolfram Barfuss, the new Argelander professor in the Innovation and Technology for Sustainable Futures Transdisciplinary Research Area (TRA Sustainable Futures) at the University of Bonn.
Discovery of the MOTH domain offers insights into evolution. This is because both insects and vertebrates need collagen in their connective tissue. Collagen is the protein that holds our body together. It is produced inside cells, from where it must be transported to its site of action in connective tissue.
Research team at Göttingen University discovers surprising properties of the cytoskeleton Most biological cells have a fixed place in an organism. However, cells can become mobile and move through the body. This happens, for example, during wound healing or when tumour cells divide uncontrollably and migrate through the body.
An international team of researchers including the University of Freiburg identifies engravings in Jordan and Saudi Arabia as the oldest known scaled building plans in human history. Although human constructions have modified natural spaces for millennia, few plans or maps predate the period of the literate civilizations of Mesopotamia and Ancient Egypt.
Around 25,000 artificial heart valves are implanted in Germany per year because the original heart valve is damaged, for example, by an infection. The mechanical heart valves are made of titanium dioxide, among other materials, and last for many years. However, because blood tends to clot on contact with these material surfaces, there is a risk of blood clots forming on the surface of mechanical heart valves.
Cis-tetrahydrocannabinoids can now be produced synthetically, enabling pharmaceutical applications A group of researchers at Leipzig University has developed a new method for synthesising cis-tetrahydrocannabinol (THC) - a natural substance found in the cannabis plant that produces the characteristic psychoactive effect and has many potential applications, including in the pharmaceutical industry.
At certain times in the year, more soot particles reach the Amazon rainforest from bush fires in Africa than from regional fires. Up to two-thirds of the soot above the central Amazon rainforest originates in Africa. These are the results of a study that has now been published in Nature Communications Earth and Environment.
Research team at the University of Freiburg traces the origin of proinflammatory cytokines Chronic myeloid leukemia (CML) is a type of blood cancer that arises from malignant changes in blood-forming cells of the bone marrow. It mainly occurs in older individuals and represents about 20 percent of all adult leukemia cases.
