Research Associate / Post-Doc in Functional Genomics and High-Throughput Sequencing

As member of our highly skilled team, you will support research groups of University departments, the University Hospital as well as larger research networks by developing and implementing novel and fit-for-purpose next generation sequencing approaches. The Core Unit SysMed offers an extensive portfolio of manual and automated library preparation and sequencing protocols used to study gene regulation of pro- or eukaryotes. More specifically, the incumbent will be involved in:

• Developing / improving an innovative and versatile platform for preparing / processing of bacterial and mammalian cDNA libraries
• Optimizing semi-automated workflows for established lab protocols for diverse transcriptome and translatome analysis methods, including (bulk, dual, differential) RNA-seq, Cappable-seq, CLIP-seq, RIL-seq, RIP-seq, Ribo-seq, Term-seq etc.
• Analysis of eukaryotic and prokaryotic data
• Maintaining end-to-end quality management during the entire preparation process of ready-to-load libraries
• Reporting and documentation of project results and milestones, consultations with users on experimental design and workplan

Applicants should have a doctoral / PhD degree and a strong background in molecular (micro)biology / biochemistry with specialization in deep sequencing approaches and transcriptomics technologies. We give preference to candidates with:

• Interest in analytical methods and laboratory techniques used in functional genomics
• Hands-on experience with operating a liquid handling robot and/or Illumina sequencer
• Additional knowledge in project management / consultation services and the willingness to become proficient in German would be beneficial